Table 2.

Time to first doubling of serum creatinine or graft loss with or without inclusion of death as a competing event, by baseline risk factors

Risk FactorHazard Ratio per Unit Difference (95% CI)P Value
Without competing risk of death
 Smoking2.04 (1.57–2.64)<0.001
 Systolic BP (mmHg)1.18 (1.06–1.30)0.003
 Creatinine1.98 (1.88–2.20)<0.001
 Diabetes mellitus1.21 (0.91–1.60)0.19
 Time since last transplant1.15 (1.03–1.29)0.03
 HLA mismatch 11.45 (1.10–1.91)0.009
 HLA mismatch 21.64 (1.17–1.91)0.004
 Hemoglobin0.78 (0.69–0.88)<0.001
 Proteinuria (score)1.30 (1.24–1.37)<0.001
With competing risk of death
 Smoking2.01 (1.51–2.66)<0.001
 Systolic BP (mmHg)1.12 (1.00–1.28)0.05
 Creatinine1.57 (1.30–1.88)<0.001
 Diabetes mellitus1.14 (0.85–1.54)0.24
 Total time since transplant1.16 (0.95–1.39)0.22
 HLA mismatch 11.35 (1.03–1.76)0.01
 HLA mismatch 21.31 (0.87–1.95)0.28
 Hemoglobin0.89 (0.81–0.92)0.001
 Proteinuria (score)1.33 (1.24–1.42)<0.001
  • There were 299 cases during 7 years of follow-up out of 1487 patients with complete data. CI, confidence interval.