Table 2.

Changes in BP and left ventricular parameters, according to follow-up time and randomization group

BaselineConventional
12 moIntensified
12 moConventional
24 moIntensified
24 moConventional Overall Follow-upIntensified Overall Follow-up
Patients (n)84151324323945
24-h MAP (mmHg)88.683.4a81.2a,b82.479.1b80.9c80.3c
24-h mean SBP (mmHg)115.3109.0a107.4a,b108.2106.8b108.9c107.7c
24-h mean DBP (mmHg)72.466.1a63.6a,b63.1d62.5b64.6c63.3c
Heart rate (min−1)82.181.080.281.279.881.279.5
BMI (kg/m2)18.017.818.217.918.517.818.4
LV mass/height2.7 (g/m2.7)33.932.631.731.630.832.0c31.0c
LV internal diameter (cm)4.224.184.04a,b4.12d4.054.14c4.05c
Relative wall thickness0.320.320.310.320.320.320.32
  • Conventional BP target aims for the 50th–95th BP percentile reference value of 24-hour MAP for height and sex. Intensified BP target aims for MAP below the 50th BP percentile reference value of 24-hour MAP for height and sex. MAP, mean arterial pressure; SBP, systolic BP; DBP, diastolic BP; BMI, body mass index; LV, left ventricular.

  • a P<0.05 comparing baseline versus 12 months.

  • b P<0.05 comparing conventional versus intensified BP target.

  • c P<0.05 comparing baseline versus overall follow-up.

  • d P<0.05 comparing 12 versus 24 months.