Table 2.

Proportional hazard analysis for patient mortality on renal replacement therapy and renal graft loss in patients with congenital anomalies of the kidney and urinary tract in the European Renal Association-European Dialysis and Transplant Association Registry

VariablePatient Mortality with RRTGraft Loss
HR (95% CI)P ValueHR (95% CI)P Value
CAKUT category
 Neurogenic PN1.66 (1.24–2.21)0.0061.32 (0.93–1.87)0.12
 Obstructive PN0.74 (0.56–0.99)0.040.95 (0.74–1.22)0.68
 Reflux PN0.75 (0.57–0.98)0.041.03 (0.79–1.32)0.85
 Hypoplasia0.73 (0.54–1.00)0.051.04 (0.77–1.40)0.81
 Dysplasia1.001.00
RRT modality at start
 Hemodialysis1.56 (1.04–2.33)0.031.02 (0.81–1.28)0.89
 Peritoneal dialysis1.29 (0.85–1.96)0.230.89 (0.69–1.14)0.37
 Pre-emptive transplantation1.001.00
Age1.06 (1.06–1.06)<0.0011.00 (1.00–1.01)0.39
Female sex1.09 (0.95–1.25)0.241.08 (0.92–1.26)0.37
Period after 20000.98 (0.86–1.13)0.810.78 (0.65–0.93)0.01
  • RRT, renal replacement therapy; HR, hazard ratio; CI, confidence interval; CAKUT, congenital anomalies of the kidney and urinary tract; PN, pyelonephritis.