Table 3.

Comparison of the performances of decision tree analysis among IgG subclasses, complements, and both in the differential diagnosis between membranous lupus nephritis and primary membranous nephropathy

MarkerSEN (%)SPC (%)PPV (%)NPV (%)ACC (%)ACC after Cross-Validation (%)
IgG subclasses92.793.290.594.893.088.0±3.3
Complements85.488.183.389.787.081.0±3.8
IgG subclasses + complements95.198.397.596.797.092.0±3.3
  • P=0.0004 for difference between IgG subclasses and complements and P<0.001 for difference between complements and IgG subclasses + complements. SEN, sensitivity; SPE, specificity; PPV, positive predictive value; NPV, negative predictive value; ACC, accuracy.