Table 2.

Diagnostic capability of serum and urine tests for cast nephropathy

SensitivitySpecificityPPVNPVAUC ROC
Urine protein (g/d)0.76
Urine M-spike (g/d)0.91
Serum albumin (g/dl)0.79
Serum creatinine (mg/dl)0.87
  • The middle values represent the best cutoff for each test which was calculated by ROC analysis. PPV, positive predictive value; NPV, negative predictive value; AUC, area under the curve; ROC, receiver operator characteristics; %UAE, percentage of urine albumin excretion; M-spike, monoclonal spike.