Table 7.

Exosome protein receiver-operating characteristic curve analysis

Protein per LevelSensitivitySpecificityAUC (95% CI)
E-cadherin0.436 (0.20–0.67)
 0.030.750.077
 0.490.4170.615
 1.160.0830.846
B-catenin0.449 (0.22–0.68)
 0.020.750.231
 2.110.4170.615
 5.580.0830.846
AQP20.583 (0.35–0.81)
 1.430.9170.231
 2.580.6670.538
 6.790.3330.923
VATPase0.615 (0.38–0.85)
 2.050.8330.077
 5.040.6670.615
 16.400.3330.846
TGFβ0.654 (0.43–0.88)
 2.420.9170.308
 3.800.750.615
 8.500.1670.769
N-cadherin0.532 (0.30–0.76)
 0.030.9170.054
 0.920.5830.538
 2.530.1670.923
L1CAM0.519 (0.28–0.75)
 1.20.9170.077
 2.080.6670.462
 8.070.0830.923
TRPV40.436 (0.18–0.69)
 1.030.9170.077
 2.710.50.385
 6.820.250.923
  • All protein levels are expressed in arbitrary units. AUC, area under the receiver-operating characteristic curve; CI, confidence interval; AQP2, aquaporin-2; VATPase, vacuolar-type H+-adenosine triphosphatase; L1CAM, L1 cell adhesion molecule; TRPV4, transient receptor potential cation channel subfamily V member 4.