Table 3.

Predictors of tumor lysis syndrome

CharacteristicRisk Factor
Tumor burdenBulky lymphatic disease (>10 cm)
Elevated lactate dehydrogenase (2× upper limit of normal)
Elevated white blood cell count (>25,000 cells/mm3)
Renal functionBaseline creatinine > 1.4 mg/dl (37)
Baseline uric acid>7.5 mg/dl
ChemosensitivityVariable
  • Adapted from reference 91.