Table 1.

Baseline characteristics by presence of vascular disease

No Vascular DiseaseVascular DiseaseP Value
Participants, n (%)1498 (87)224 (13)
Age (yr), mean49.460.2<0.001
Female (%)42.421.4<0.001
African-American race (%)12.98.50.10
Systolic BP (mmHg), mean131.7137.9<0.001
Diastolic BP (mmHg), mean81.878.7<0.001
LDL cholesterol (mg/dl), mean147.8148.80.70
HDL cholesterol (mg/dl), mean40.535.5<0.001
Body mass index >30 (%)24.129.50.10
Current smoking (%)12.111.60.80
Diabetes (%)4.914.3<0.001
Cause of renal disease (%)
 GN33.225.4<0.001
 Polycystic kidney disease23.314.3
 Other43.560.3
Measured GFR (mean), ml/min per 1.73 m239.735.40.01
CKD-EPI GFR (mean), ml/min per 1.73 m238.833.9<0.001
Estimated GFR (%)
 60–7410.27.10.1
 45–5919.517.4
 30–4427.226.3
 15–2927.333.5
 0–1410.614.2
Proteinuria (mg/d), median (IQR)29 (6–131)24 (6–166)0.10
Reached ESRD (%)65.055.80.01
Died before ESRD (%)11.630.8<0.001
Died after ESRD onset (%)26.447.3<0.001
  • CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration; IQR, interquartile range.