Table 3.

Association between prescription patterns and achievement in target levels of phosphorus and calcium

Prescription PatternACa (pg/ml)Proportionb (%)PDc95% CI
CinacalcetVDRA
Phosphorus (4026 sets)
NotDecreased−0.2964.00.03−0.02 to 0.07
NotStable−0.1260.9Reference
NotIncreased−0.0161.60.00−0.03 to 0.04
StartingDecreased−0.8272.50.120.04–0.20
StartingStable−0.4961.20.03−0.02 to 0.09
StartingIncreased−0.3567.40.070.00–0.15
Calcium (4027 sets)
NotDecreased−0.1462.60.01−0.03 to 0.05
NotStable0.1365.5Reference
NotIncreased0.3265.4−0.02−0.06 to 0.01
StartingDecreased−0.6965.70.090.01–0.17
StartingStable−0.3569.30.080.02–0.14
StartingIncreased−0.1660.30.03−0.05 to 0.11
  • VDRA, vitamin D receptor activator; AC, absolute change; PD, proportion difference; 95% CI, 95% confidence interval; iPTH, intact parathyrpid hormone.

  • a Means of AC between reference and outcome visits.

  • b Proportions of patients with achievement of target levels.

  • c Adjusted for age, sex, dialysis duration, intact PTH levels, phosphorus levels, calcium levels, use of calcium- or non–calcium-based phosphate binders, single-pool Kt/V, and dialysate calcium.