Table 4.

Characteristics of incident ESRD among validated symptomatic stone formers compared with ESRD among control participants in Olmsted County, Minnesota

CharacteristicStone Formers Who Developed ESRD (n=34), n (%)Controls Who Developed ESRD (n=75), n (%)P Value
(Fisher’s Exact Test)
Primary cause of ESRD
 diabetes mellitus6 (18)22 (29)0.24
 hypertension6 (18)13 (17)1.0
 GN4 (12)10 (13)1.0
 cystic kidney disease2 (6)3 (4)0.64
 urolithiasis4 (12)0 (0)0.008
 other urologic disease6 (18)3 (4)0.03
 other known cause4 (12)19 (25)0.13
 unknown cause2 (6)5 (7)1.0
Comorbidities present before onset of ESRD
 diabetes mellitus11 (32)37 (49)0.14
 hypertension15 (44)39 (52)0.54
 recurrent urinary tract infections9 (26)3 (4)0.001
 acquired single kidney5 (15)2 (3)0.03
 ileal conduit3 (9)0 (0)0.03
 neurogenic bladder4 (12)1 (1)0.03
 hydronephrosis15 (44)3 (4)<0.001