Table 4.

Selected pharmacokinetic parameters grouped according to peritoneal membrane transporter status

ParameterLow AverageHigh AverageHighP Valuear2
F0.640.780.760.030.30
t1/2, eq (hours)5.602.382.940.040.48
  • All values are reported as median. F, fraction of intraperitoneal dose absorbed; t1/2, eq, equilibration half-life.

  • a Linear regression analysis after transformation of data to normal distribution.