Table 4.

Hospital course and outcomes in patients with acute kidney injury by statin use

CharacteristicaAll Patients With AKI (n=631)AKI With Prehospital Statin Use (n=176)AKI Without Prehospital Statin Use (n=455)P ValueAKI With Continued Statin Use (n=144)AKI Without Continued Statin Use (n=487)P Value
Developed severe sepsis329 (52.1)76 (43.1)253 (55.6)0.00562 (43)267 (54.8)0.01
ICU admission245 (38.8)62 (35.23)183 (40.2)0.2447 (32.6)198 (40.6)0.08
Mechanical ventilation116 (18.3)25 (14.2)91 (20)0.0917 (11.8)99 (20.3)0.02
Median length of hospital stay (d) (IQR)8 (5–12)7 (5–11)8 (5–13)0.127 (5–11)8 (5–12)0.35
RRT during CAP hospitalization16 (2.5)5 (2.8)11 (2.4)0.762 (1.4)14 (2.9)0.32
RRT at 1 yr among survivors8 (2)08 (2.8)0.1108 (2.7)0.12
1-yr mortality229 (36.2)52 (29.5)177 (38.9)0.0240 (27.8)189 (38.8)0.01
  • Unless otherwise stated, data are the number (percentage) of patients. AKI, acute kidney injury; ICU, intensive care unit; IQR, interquartile range; CAP, community-acquired pneumonia; RRT, renal replacement therapy.

  • a Hospital course and outcome in the entire cohort of 631 patients with community-acquired pneumonia who developed acute kidney injury, by statin use.