Table 2.

Algorithm’s recommendations for parathyroid hormone level greater than 450 pg/ml

QuarterIncrease in Cinacalcet DoseIncrease in Active Vitamin D DoseDo Not Increase Cinacalcet Dose Because of:
Low CalciumPTH VariabilityPTH DecreasingIntoleranceOff MedicationMaximum Dose
1st40.215.223.713.601.62.73.3
2nd34.823.222.57.33.63.60.74.4
3rd30.816.527.16.76.06.02.34.5
4th26.721.130.05.65.66.71.13.3
  • Values are percentage of patients who had their medications adjusted as indicated. “Off Medication” indicates that a patient was not taking the prescribed cinacalcet dose and therefore did not have the medication dose increased. “Maximum Dose” indicates that a patient was taking 180 mg of cinacalcet daily. PTH, parathyroid hormone.