Table 1.

Frequency of renal insufficiency at baseline and year 8

Renal Insufficiency 
EndpointBaseline (%)Year 8 (%)
GFR (CKD stage)
 <30 stage 40 (0.0)24 (10.0)
 30–<60 stage 310 (4.2)50 (20.7)
 60–<90 stage 294 (39.8)65 (27.0)
 ≥90 stage 1132 (55.9)102 (42.3)
 GFR decreased >20%136 (56.4)
 GFR decreased >40%63 (26.1)
eGFR (MDRD formula)
 <300 (0.0)26 (10.8)
 30–<6024 (10.0)61 (25.3)
 60–<90121 (50.2)81 (33.6)
 ≥9096 (39.8)73 (30.3)
 eGFR decreased >20%132 (54.8)
 eGFR decreased >40%63 (26.1)
  • GFR measured in milliliters per minute per 1.73 m2. eGFR, estimated GFR; MDRD, Modified Diet in Renal Disease formula.