Table 1.

Cohort characteristics

Characteristicn = 249
Demographics
    age ≥65 years143 (57)
    male gender143 (57)
    non-Caucasian race59 (24)
    body mass index29.9 ± 8
Clinical characteristics
    pre-existing CKD62 (25)
    hypertension171 (69)
    diabetes102 (41)
    CHF92 (37)
    CAD102 (41)
    COPD49 (20)
    stroke34 (14)
    dementia20 (8)
    liver failure/cirrhosis27 (11)
    active cancer60 (24)
    OSA21 (8)
Number of comorbidities
    none17 (7)
    134 (14)
    ≥2198 (79)
Tobacco use
    never130 (52)
    prior60 (24)
    current42 (17)
Enrollment location
    ICU120 (48)
    floor129 (52)
Kidney function
    baseline SCr (mg/dL)1.2 ± 0.5
    baseline GFRa68.5 ± 30
Stage of AKI at enrollment
    stage 1207 (83)
    stage 242 (17)
Stage of AKI at peak SCr
    stage 1176 (71)
    stage 241 (16)
    stage 318 (7)
    stage 3-dialysisb14 (6)
Oliguria/anuria39 (16)
Day 0 SCr (mg/dl)1.8 ± 0.60
Peak SCr (mg/dl)2.2 ± 1.1
Discharge SCr (mg/dl)1.4 ± 0.7
Length of AKI (days)6.9 ± 11
Length of stay (days)20 ± 26
AKI etiology by chart review
    ATN51 (20)
    prerenal azotemia164 (66)
    other34 (14)
  • The values presented as n (%) or mean ± SD. AKI, acute kidney injury; ATN, acute tubular necrosis; CKD, chronic kidney disease (if specifically listed in patient medical history); CHF, congestive heart failure; CAD, coronary artery disease; COPD, chronic obstructive pulmonary disease; OSA, obstructive sleep apnea; ICU, intensive care unit; SCr, serum creatinine.

  • a GFR (in ml/min per 1.73 m2) was estimated by the Modification of Diet in Renal Disease equation.

  • b Those acutely dialyzed for AKI; excludes those with stage 3 AKI who were not dialyzed.