Table 2.

Cox regression analysis

UnivariateSimple AdjustmentaExtended Adjustmentb
HR (95% CI)PHR (95% CI)PHR (95% CI)P
Including only main effects of phosphorus and albumin
    phosphorus (mmol/L)1.09 (0.75 to 1.58)0.671.47 (0.96 to 2.25)0.081.57 (0.97 to 2.54)0.07
    albumin (g/dl)0.21 (0.15 to 0.29)<0.0010.19 (0.13 to 0.28)<0.0010.23 (0.14 to 0.36)<0.001
Including main effects of phosphorus and albumin + interaction effect
    phosphorus-albumin0.0040.01
  • Hazard ratios (HRs), 95% confidence intervals (CIs), and P-values of continuous and time-varying phosphorus and albumin concentrations as well as of their interaction term each in a univariate Cox model, in a simple adjustment model (adjusted for age, gender, and type of dialysis therapy) and an extended adjustment model (adjusted for age, gender, type of dialysis therapy, C-reactive protein, hemoglobin, calcium, and immunoreactive parathyroid hormone [iPTH]) on all-cause mortality risk.

  • a Adjusted for age, gender, type of dialysis therapy.

  • b Adjusted for age, gender, type of dialysis therapy, C-reactive protein, hemoglobin, calcium, and iPTH.