Table 3.

Coefficients of the intercepts and slopes of the eGFR progression analysis

Coefficient (95% CI)P
Variables that affect the intercept
Intercept80.9 (80.7, 81.1)<0.01
    Age (decades)−5.1 (−5.2, −5.0)<0.01
    Female gender (versus male)1.2 (1.0, 1.4)<0.01
Race/ethnicity
    African American4.1 (3.6, 4.6)<0.01
    Hispanic/Latino3.7 (3.2, 4.2)<0.01
    Caucasian (referent)1.0
    other1.7 (1.0, 2.3)<0.01
    missing1.0 (0.7, 1.2)<0.01
Diabetes2.9 (2.6, 3.2)<0.01
Systolic BP, time-weighted (per 10 mmHg)0.2 (0.2, 0.3)<0.01
HDL, time-weighted (per 10 mg/dl)0.2 (0.1, 0.3)<0.01
Variables that affect the slope
    Time (years)−1.4 (−1.4, −1.3)<0.01
    Age (decades)−0.2 (−0.2, −0.2)<0.01
    Female gender (versus male)−0.8 (−0.8, −0.7)<0.01
    Diabetes−0.8 (−0.9, −0.7)<0.01
    Congestive heart failure−0.3 (−0.5, −0.2)<0.01
    Systolic BP, time-weighted (per 10 mmHg)−0.2 (−0.2, −0.2)<0.01
    HDL, time-weighted (per 10 mg/dl)0.1 (0.0, 0.1)<0.01
  • The intercept coefficients represent the within-subgroup difference in baseline estimated GFR (eGFR). The slope coefficients represent the rate of change of eGFR per year, where a negative number represents a decline in kidney function. CI, confidence interval.