Table 3.

Significant Correlations with SAF

Total CohortDMNo DM
rP-valuerP-valuerP-value
eGFR (ml/min per 1.73m2)−0.228<0.01−0.1890.01−0.210<0.01
Hemoglobin (g/dl)−0.228<0.01−0.331<0.01−0.172<0.01
Age (years)0.213<0.010.1500.010.225<0.01
Total cholesterol (mmol/L)−0.150<0.01−0.1320.03−0.089<0.01
Smoking history (pack years)0.174<0.010.1340.020.174<0.01
Urine PCRa0.173<0.010.218<0.010.124<0.01
Urine ACRa0.129<0.010.1930.010.078<0.01
Diastolic BP (mmHg)−0.149<0.01−0.171<0.01−0.107<0.01
Albumin (mmol/L)−0.125<0.01−0.144<0.01−0.117<0.01
PWV (m/s)0.120<0.010.1200.050.099<0.01
HS CRP (units)a0.115<0.010.0530.37b0.126<0.01
Waist:hip ratio0.111<0.010.1810.0020.063<0.01
Uric acid (μmol/L)0.071<0.01−0.0380.53b0.076<0.01
IMD score0.069<0.010.0110.86b0.082<0.01
Bicarbonate (mmol/L)−0.063<0.01−0.1010.09b−0.0280.29b
HDL cholesterol (mmol/L)−0.0570.02−0.1180.05−0.0100.70b
  • SAF, skin autofluorescence; DM, diabetes mellitus; ACR, albumin to creatinine ratio; eGFR, estimated GFR; hsCRP, high-sensitivity C-reactive protein; IMD, indices of multiple deprivation; PCR, protein to creatinine ratio; PWV, pulse wave velocity.

  • a Not statistically significant.

  • b Log-transformed data.