Table 1.

Clinical characteristic at the time of biopsy and last follow-up

VariablesNo Doubling Serum Creatinine or ESRD (n = 147)Doubling Serum Creatinine or ESRD (n = 36)P
Age at biopsy (years)40 ± 1557 ± 15<0.001
Proteinuria at biopsy (g/d)0.89 ± 1.182.79 ± 1.77<0.001
Proteinuria at biopsy (<1, 1 to 3, >3 g/d)102, 36, 99, 12, 15<0.001
Hypertension at biopsy30%71%<0.001
eGFR at biopsy (ml/min per 1.73 m2)82 ± 2531 ± 24<0.001
CKD stage at biopsy (1, 2, 3, 4, 5)54, 63, 26, 4, 01, 3, 11, 9, 12<0.001
Follow-up duration (months)83 ± 5339 ± 42<0.001
eGFR at last follow-up (ml/min per 1.73 m2)74 ± 2410 ± 9<0.001
RAS blockade48%56%0.04
Steroids13%32%0.004
  • The data are expressed as means ± SD, numbers, or percentages. eGFR was calculated using altered Modification of Diet in Renal Disease. eGFR, estimated GFR; RAS, renin angiotensin system.