Table 1.

Demographics and laboratory data of patients vaccinated against 2009 pandemic influenza virus

Non-Seroprotected Vaccinated Renal Patients (n = 85) Non-Seroprotected Vaccinated Transplant Patients (n = 55)Non-Seroprotected Vaccinated Hemodialysis Patients (n = 30)
SCV (n = 33)Non-SCV (n = 52)SCV (n = 23)Non-SCV (n = 32)SCV (n = 10)Non-SCV (n = 20)
Age (years)54.67 ± 15.0863 ± 15.954.22 ± 12.3557.59 ± 15.3655.7 ± 20.8471.65 ± 10.09
Gender (male/female)20/1334/1812/1121/118/213/7
Weight (kg)70.04 ± 14.2171.23 ± 14.5672.52 ± 12.8574.83 ± 15.42
Seasonal vaccine (yes/no)25/89/4317/627/58/216/4
Time after transplant (months)62.12 (12.97; 159.37)31.34 (8.93; 60.197)
Creatinine pre vaccine (mg/dl)1.95 ± 0.621.85 ± 0.53
MDRD-GFR pre vaccine (ml/min/1.73 m2)43.55 ± 19.1544.19 ± 14.70
Serum proteins (g/L)7.4 (7.12; 8)7.4 (7.1; 7.8)7.4 (7.2; 8)7.4 (7.1; 7.67)7.5 (6.35; 8.15)7.6 (6.4; 8.2)
Serum albumin (g/L)4.24 ± 0.364.21 ± 0.634.33 ± 0.274.36 ± 0,404.03 ± 0.473.92 ± 0.88
Proteinuria pre vaccine (mg/day)186 (106; 514)159 (117; 235)
Hemoglobin (g/dl)12.8 (11.45; 14.05)13.1 (12.1; 13.8)12.9 (11.5; 14.1)13.5 (12.32; 13.9)12.55 (10.2; 14)12.4 (11.1; 13.5)
Leukocytes 103/mm37.521 ± 2.7987.328 ± 2.3318.235 ± 3.0117.618 ± 2.4085.880 ± 1.1796.839 ± 2.170
Ferritine (mg/dl)238 (59.5; 341.5)255 (136; 470)149 (39; 264)211 (47; 321)272.5 (119; 366.25)320.5 (194.5; 503.5)
PTH (pg/ml)152.5 (66.75; 203)112 (62.75; 207.25)125 (66.75; 191.5)83 (59; 138)172 (82; 497)200 (107; 391)
Creatinine post vaccine (mg/dl)2.00 ± 1.151.75 ± 0.76
Proteinuria post vaccine (mg/day)158 (124.5; 727.75)192 (122; 270)
Steroid treatment (yes/no)14/920/12
Tacrolimus treatment (yes/no)20/228/4
Tacrolimus dose (mg/day)4.45 ± 2.864.16 ± 2.38
Tacrolimus trough levels (ng/ml)9.23 ± 2.419.12 ± 2.59
Treatment with MPA (yes/no)16/627/5
MPA trough levels (mcg/ml)1.85 (1.7; 2.35)2.15 (1.6; 2.67)
Kt/V single pool (dose of dialysis)1.63 ± 0.321.81 ± 0.29
Time on dialysis (months)25.35 ± 23.1343.98 ± 42.3
  • All data are pre vaccine, except for those marked as post vaccine. Normal variables are expressed as mean ± standard deviation; not normal variables are expressed as median (75th percentile; 25th percentile range). SCV, seroconversion; MDRD GFR, modification of diet in renal disease study equation for estimating glomerular filtration rate; PTH, parathyroid hormone; MPA, mycophenolate.