Table 5.

Age-adjusted OR per 1 SD decrease and the area under the ROC curve for imaging parameters in patients with fractures

OR (95% CI)PArea under ROC Curve (95% CI)P
HR-pQCT tibia
    Dtot2.86 (1.29 to 5.80)0.010.87 (0.77 to 0.98)<0.01
    Dcort1.89 (1.02 to 3.57)0.040.84 (0.69 to 0.96)<0.01
    CtTh2.56 (1.30 to 5.00)0.010.86 (0.76 to 0.97)<0.01
    Dtrab3.70 (1.59 to 8.33)0.010.90 (0.80 to 0.99)<0.01
    BV/TV3.45 (1.52 to 8.33)0.010.89 (0.79 to 0.99)<0.01
    TbN2.86 (1.39 to 5.88)0.010.88 (0.77 to 0.98)<0.01
    TbTh1.04 (0.63 to 1.61)0.950.83 (0.69 to 0.95)<0.01
    Tb1/NSD0.28 (0.11 to 0.72)0.010.89 (0.79 to 0.99)<0.01
HR-pQCT radius
    Dtot1.82 (0.99 to 3.33)0.060.84 (0.71 to 0.96)<0.01
    Dcort1.27 (0.74 to 2.13)0.390.83 (0.69 to 0.96)<0.01
    CtTh1.85 (1.01 to 3.33)0.050.83 (0.70 to 0.96)<0.01
    Dtrab2.17 (1.12 to 4.17)0.020.84 (0.72 to 0.96)<0.01
    BV/TV2.17 (1.12 to 4.17)0.020.83 (0.70 to 0.96)<0.01
    TbN2.86 (1.37 to 5.56)0.010.85 (0.72 to 0.98)<0.01
    TbTh1.33 (0.76 to 2.33)0.310.84 (0.72 to 0.96)<0.01
    Tb1/NSD0.49 (0.29 to 0.83)0.010.87 (0.76 to 0.98)<0.01
DXA
    femoral neck aBMD2.04 (1.04 to 3.85)0.040.84 (0.71 to 0.97)<0.01
    lumbar spine aBMD1.96 (0.99 to 3.85)0.060.84 (0.71 to 0.97)<0.01
    radius aBMD3.33 (1.35 to 8.33)0.010.85 (0.73 to 0.97)<0.01
  • OR, odds ratio; ROC, receiver-operating characteristic; CI, confidence interval; HR-pQCT, high-resolution peripheral quantitative computed tomography; Dtot, total density; HA, hydroxyapatite; Dcort, cortical density; CtTh, cortical thickness; Dtrab, trabecular thickness; BV/TV, trabecular bone volume; TbN, trabecular number; TbTh, trabecular thickness; Tb1/NSD, SD of 1/TbN; DXA, dual-energy x-ray absorptiometry; aBMD, areal bone mineral density.