Table 6b.

Prevalence ratios by level of GFR, excluding medication use

Medical ConditionnCKiD GFR Categories,a ml/min per 1.73 m2
≥50 (reference)≥40 to <50, Estimate (95% CI)≥30 to <40, Estimate (95% CI)<30, Estimate (95% CI)
Elevated potassium (>5.2 mEq/L)56612.09 (0.91, 4.83)2.21 (0.97, 5.01)4.69 (2.23, 9.86)
Acidotic (CO2 <21 mEq/L)b41511.80 (1.12, 2.89)2.25 (1.41, 3.61)2.73 (1.72, 4.33)
Elevated phosphatec45511.57 (0.64, 3.84)2.02 (0.85, 4.81)5.68 (2.65, 12.14)
Growth failure (height <3rd percentile)50211.81 (0.93, 3.53)2.27 (1.20, 4.33)2.62 (1.36, 5.05)
Anemia (excluding ESA use only)49511.68 (1.07, 2.66)2.66 (1.76, 4.00)3.85 (2.59, 5.72)
Anemia (excluding ESA and iron use)38411.83 (1.05, 3.17)2.79 (1.67, 4.67)4.10 (2.51, 6.70)
Hypertension (BP ≥95th percentile for age and gender or self-reported hypertension and on a antihypertensive medication)56511.00 (0.80, 1.26)1.04 (0.83, 1.29)1.36 (1.12, 1.65)
High cholesterold48911.47 (0.96, 2.26)1.77 (1.18, 2.64)1.55 (0.98, 2.45)
  • CKiD, Chronic Kidney Disease in Children study; CI, confidence interval; ESA, erythropoiesis stimulating agent.

  • a Prevalence ratio estimation determined using Poisson regression with robust error variance.

  • b On the basis of locally measured values of CO2.

  • c On the basis of the phosphate norms reported in reference 29.

  • d On the basis data from reference 28.