Table 1.

Patient and renal survival on the basis of era of initial treatment regimen

EranWHO Classification (n)TreatmentRenal Survival (%)5-Year Patient Survival (%)
IIIIVV2-Year5-Year
1173122Triple oral therapy: CS + AZA + CYC825283
2241194iv-CYC625187
3314206MMF ± iv CYC969197
4231184RTX ± iv CYC ± MMF958891
  • Low-dose maintenance CS was used in all eras. Pulse intravenous methylprednisolone was used in eras 2 to 4. WHO, World Health Organization; AZA, azathioprine; CYC, cyclophosphamide; CS, corticosteroids; iv, intravenous; MMF, mycophenolate mofetil; RTX, rituximab.