Table 1.

Patient characteristics at enrollment

CharacteristicsSevelamer (n = 30)Calcium acetate (n = 29)
Sex (male/female)15/1514/15
Age (years)59.6 ± 16.962.8 ± 14.1
Diabetics43%41%
Time on HD (months)30 ± 1028 ± 11
Calcium (mg/dl)9.0 ± 0.79.0 ± 0.5
Phosphate (mg/dl)5.4 ± 1.05.1 ± 0.6
Ca x P (mg2/dl2)49.9 ± 13.046.5 ± 6.4
Intact PTH (pg/ml)247 ± 92258 ± 145
C-reactive protein (mg/L)6.9 (5 to 9.8)5.9 (4.7 to 6)
TNF-α (pg/ml)8 (6 to 8.4)6.4 (5.8 to 8.7)
Interleukin-1 (pg/ml)0.8 (0.5 to 1.2)1.2 (0.8 to 1.4)
Interleukin-6 (pg/ml)5 (3 to 9.1)4.9 (4 to 8.1)
Interleukin-10 (pg/ml)75 (52 to 98)77 (71 to 94)
Interleukin-18 (pg/ml)599 (514 to 635)526 (420 to 621)
Endotoxin (EU/ml)0.58 (0.51 to 0.60)0.60 (0.51 to 0.63)
Soluble CD14 (μg/ml)2.94 (1.76 to 5.29)2.88 (2.35 to 4.70)
  • Values represent the mean ± the SDs, or the median and interquartile ranges in parentheses. HD, hemodialysis, PTH, parathyroid hormone.