Table 2a.

Characteristics of the patients in the medicine and surgery wards

CharacteristicsnrHA-AKI (n = 958)lrHA-AKI (n = 2504)erHA-AKI (n = 834)Pa
Age, years62 ± 1661 ± 1360 ± 170.93
    20 to 3973 (7.6)300 (12)217 (26)<0.01
    40 to 59297 (31)626 (25)325 (39)0.03
    60 to 79469 (49)1302 (52)234 (28)0.02
    ≥80119 (12.4)275 (11)58 (7)0.01
Women412 (43)1127 (45)367 (44)0.81
Men546 (57)1402 (55)467 (56)0.85
Hospitalization
    medicine ward642 (67)1527 (61)275 (33)0.002
    surgery ward316 (33)977 (39)559 (67)0.003
Comorbidity
    hypertension489 (51)1227 (49)417 (50)0.76
    diabetes mellitus240 (25)626 (25)192 (23)0.69
    cardiovascular disease220 (23)526 (21)183 (22)0.71
    acute infection172 (18)551 (22)158 (19)0.59
    neoplasia77 (8)225 (9)83 (10)0.51
    chronic obstructive pulmonary disease96 (10)250 (10)67 (8)0.64
    liver disease48 (5)150 (6)50 (6)0.69
    AIDS48 (5)100 (4)42 (5)0.73
Charlson Comorbidity Score6.5 ± 2.75.1 ± 3.25.3 ± 2.60.03
Median baseline SCr (μmol/L)131 (75 to 246)121 (68 to 237)131 (71 to 256)0.12
Median baseline eGFR (ml/min per 1.73 m2)59 (121 to 24)61 (103 to 29)60 (123 to 24)0.19
AKIN stage
    1572 (60)952 (38)218 (26)0.01
    2357 (37)825 (33)396 (47)0.02
    329 (3)727 (29)220 (26)<0.01
Median SCr at first nephrologic evaluation (μmol/L)NA345 (127 to 1542)292 (143 to 1845)0.01
Mean SCr at first dialysis (μmol/L)NA735 ± 213532 ± 1050.01
RRT patients during hospital stayNA776 (31)200 (24)0.01
Oliguriab48 (5)426 (17)158 (19)0.03
Mortality rate during hospital stay211 (22)526 (21)100 (12)0.01
  • Values are expressed as number (percent), mean ± SD, or median (range). nrHA-AKI, hospital acquired-acute kidney injury without nephrology referral; lrHA-AKI, late-referred HA-AKI; erHA-AKI, early-referred HA-AKI; eGFR: estimated GFR by the abbreviated four-variable Modification of Diet in Renal Disease equation; AKIN, Acute Kidney Injury Network; RRT, renal replacement therapy; NA, not assessed.

  • a Group-wise differences were calculated using ANOVA with Bonferroni correction when necessary.

  • b Oliguria was defined as urinary output <500 ml/24 h.