Table 2.

Age-stratified hazard ratios for all-cause mortality associated with eGFR

Age Group, Years
45 to 59.960 to 69.970 to 79.9≥80
Age, race, gender, and region adjusted hazard ratios (95% CI)
    eGFR, ml/min per 1.73 m2
        ≥601 (ref)1 (ref)1 (ref)1 (ref)
        45 to 59.93.9 (2.1 to 7.0)2.4 (1.8 to 3.1)1.3 (1.1 to 1.6)1.6 (1.3 to 2.1)
        <457.8 (4.5 to 13.6)4.5 (3.4 to 6.2)3.1 (2.5 to 3.8)2.2 (1.7 to 2.9)
    P trend<0.01<0.01<0.01<0.01
Multivariable adjusted hazard ratios (95% CI)
    eGFR, ml/min per 1.73 m2
        ≥601 (ref)1 (ref)1 (ref)1 (ref)
        45 to 59.92.5 (1.3 to 4.6)1.7 (1.3 to 2.3)1.1 (0.9 to 1.3)1.3 (1.0 to 1.7)
        <453.5 (1.8 to 6.8)2.2 (1.6 to 3.0)1.9 (1.5 to 2.4)1.5 (1.1 to 2.0)
    P trend<0.01<0.01<0.01<0.01
  • Multivariable adjusted includes age, gender, race, region, education, physical activity, income, current smoking, general health status, waist circumstance, systolic BP, diastolic BP, antihypertensive medication use, diabetes mellitus, LDL cholesterol, HDL cholesterol, statin use, high sensitivity C-reactive protein ≥ 2 mg/L, history of coronary heart disease, self-reported stroke, atrial fibrillation, and albuminuria. CI, confidence interval; eGFR, estimated GFR; ref, reference.