Table 4.

Percentage bias (95% confidence interval) of eGFR calculated using the CKD-EPI equation and MDRD equation with mGFR by iothalamate renal clearance by age group

EquationAge GroupPotential Kidney DonorsPostnephrectomy Kidney DonorsNative CKDKidney RecipientsOther Organ Recipients
CKD-EPI<40 years−8% (−10%, −5%)a18% (10%, 27%)12% (8%, 16%)14% (7%, 21%)
40 to 69 years−9% (−11%, −7%)−9% (−13%, −5%)4% (1%, 6%)7% (5%, 8%)9% (6%, 12%)
>70 yearsaa5% (2%, 8%)10% (5%, 14%)8% (1%, 14%)
MDRD<40 years−19% (−22%, −17%)a8% (0%, 16%)1% (−3%, 4%)2% (−5%, 8%)
40 to 69 years−17% (−19%, −16%)−17% (−20%, −13%)0% (−2%, 2%)0% (−2%, 1%)3% (0%, 5%)
>70 yearsaa9% (5%, 12%)11% (6%, 15%)8% (1%, 15%)
  • The percentage bias was calculated as follows: {Σ [(eGFR − mGFR)/mGFR]}/n. CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration; MDRD, Modification of Diet in Renal Disease; eGFR, estimated GFR.

  • a Group contained <10 persons to estimate bias.