Table 1.

Baseline demographics of subjects with normotension compared with those with EBP

CharacteristicNormal BP (n = 251)EBP (n = 132)P
Age (years)a13 (10 to 15)13 (10 to 15)0.94
Male gender152 (61%)78 (59%)0.83
African American race46 (18%)30 (23%)0.35
Hispanic35 (14%)20 (16%)0.76
BMI percentilea61 (31 to 85)70 (41 to 91)0.03
Maternal education (college or more)76 (31%)39 (30%)0.81
iGFRa44 (34 to 56)41 (30 to 54)0.19
Low birth weight45 (19%)22 (17%)0.78
% of life with CKDb92 (43 to 100)70 (21 to 99)0.01
CKD duration (years)a9 (5 to 12)7 (3 to 11)0.03
Treated hypertension68%71%0.64
Glomerular CKD diagnosis57 (23%)40 (31%)0.12
Nephrotic proteinuria34 (14%)23 (18%)0.29
Hemoglobin (g/dl)a12 (12 to 14)12 (11 to 14)0.78
SBP indexa0.84 (0.80 to 0.89)0.97 (0.92 to 1.00)<0.01
DBP indexa0.80 (0.73 to 0.87)0.96 (0.90 to 1.01)<0.01
  • Normal BP = SBP and DBP < 90th percentile; Elevated BP = SBP and/or DBP ≥ 90th percentile. EBP, elevated BP; SBP, systolic BP; DBP, diastolic BP; BMI, body mass index; CKD, chronic kidney disease; iGFR, GFR determined by plasma iohexol disappearance; IQR, interquartile range.

  • a Median (IQR).

  • b Duration is shown as percentage of life with CKD (%, IQR).