Table 5.

Percentage bias (95% confidence interval) of eGFR calculated using the CKD-EPI equation and MDRD equation with mGFR by iothalamate renal clearance by gender

EquationGender<40 years old40 to 69 years old≥70 years old
Before and after Kidney DonationCKD and Transplant RecipientsBefore and after Kidney DonationCKD and Transplant RecipientsBefore and after Kidney DonationCKD and Transplant Recipients
CKD-EPIMale−6.9% (−10.6%, −3.2%)19.2% (13.2%, 25.3%)−9.5% (−11.8%, −7.3%)6.7% (4.8%, 8.7%)a7.4% (4.0%, 10.7%)
Female−7.2% (−10.6%, −3.9%)11.0% (4.5%, 17.6%)−8.6% (−10.6%, −6.7%)5.4% (3.7%, 7.1%)a4.4% (1.2%, 7.4%)
MDRDMale−17.8% (−21.4%,−14.2%)8.9% (3.3%, 14.5%)−16.3% (−18.5%, −15.8%)1.0% (−0.7%, 2.6%)a11.5% (7.9%, 15.0%)
Female−19.6% (−22.8%, −16.4%)−1.5% (−7.6%, 4.5%)−17.6% (−19.5%, −15.8%)−0.4% (−2.3%, 1.5%)a5.3% (2.2%, 8.5%)
  • The percentage bias was calculated as follows: {Σ [(eGFR − mGFR)/mGFR × 100%]}/n. CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration; MDRD, Modification of Diet in Renal Disease; eGFR, estimated GFR; mGFR, measured GFR.

  • a Group contained <10 persons to estimate bias.