Table 1.

Baseline characteristics of the trial population

Median (IQR)P Values for the Difference
Experimental Intervention (n = 238)Standard Care Control (n = 236)
Age (years)67 (62, 72)67 (61, 72)0.85
Baseline serum creatinine (╬╝mol/L)127 (112, 145)128 (114, 143)0.85
Baseline eGFR (ml/min per 1.73 m2)42 (40, 46)42 (37, 46)0.78
Weight (kg)83 (72, 96)82 (72, 91)0.33
Systolic BP128 (116, 140)132 (120, 144)0.001
Diastolic BP74 (66, 80)74 (68, 81)0.96
Proteinuria (g/day)0.11 (0.07, 0.2)0.12 (0.08, 0.22)0.06
LDL cholesterol (mmol/L)2.6 (2.1, 3.3)2.7 (2.1, 3.5)0.07
Hba1c among diabetics (%)6.9 (6.4, 7.9)7.1 (6.3, 7.6)0.58
Hemoglobin (g/L)136 (125, 144)134 (126, 144)0.33
Number (%)Number (%)
Female131 (55)132 (56)0.85
Caucasian223 (94)224 (95)0.28
Retired144 (61)158 (67)0.15
Working58 (24)55 (23)0.42
Post-secondary school education96 (40)100 (42)0.90
Married/living as married167 (70)154 (65)0.37
Living in own home, no hired assistance224 (94)219 (93)0.77
Current smoker18 (8)18 (8)1.0
Systolic BP >130 mmHg84 (36)120 (51)0.001
Systolic BP >140 mmHg61 (26)81 (35)0.05
Diastolic BP >80 mmHg40 (17)60 (26)0.03
Diastolic BP >90 mmHg10 (4)11 (5)0.98
Diabetes mellitus73 (31)76 (33)0.65
Angina19 (8)28 (12)0.21
History of myocardial infarction39 (17)33 (14)0.55
History of PTCA26 (11)20 (9)0.46
History of CABG25 (11)19 (8)0.45
History of heart failure13 (6)9 (4)0.53
History of cardiac arrhythmia32 (14)32 (14)1.0
History of cerebrovascular event10 (4)15 (7)0.40
History of hypertension182 (78)178 (77)0.87
History of chronic lung disease46 (20)49 (21)0.78
History of cancer34 (15)40 (17)0.50
Taking an ACE inhibitor or ARB165 (70)156 (66)0.51
Taking a statin118 (25)103 (22)0.23
  • PTCA, percutaneous transluminal coronary angioplast; CABG, coronary artery bypass graft; ACE, angiotensin-converting enzyme; ARB, angiotensin II receptor blocker. Continuous variables are presented as medians (intraquartile range). Binary variables are presented as numbers (percentages).