Table 2.

Demographics

CategoryNo AKI (n = 357)AKI (n = 357)pRIFLE R (n = 291)pRIFLE I (n = 65)pRIFLE F (n = 1)
Age (years)7.7 ± 5.46.7 ± 5.6a6.8 ± 5.6a6.0 ± 5.56
Age category (patients)
    Neonates (1 to 30 days)11100
    Infants (>30 days to 2 years)404030100
    Children (> 2 to 12 years)233233189431
    Adolescents (>12 years)838371120
Baseline eCCl (ml/min per 1.73 m2)139.5 ± 43161.1 ± 78.5a152.9 ± 42.9a199.7 ± 144.6a29.9
Minimum eCCl (ml/min per 1.73 m2)135 ± 41.8125.4 ± 46.5a125.5 ± 37.7a126.7 ± 73.623.9
Maximum eCCl (ml/min per 1.73 m2)164 ± 45.3209.7 ± 94.5a190.2 ± 54.4a299.9 ± 160.5a29.9
Length of hospital stay (days)7.1 ± 4.212.3 ± 9.4a11.5 ± 8.3a16.1 ± 12.5a4
Cost of stay (U.S. dollars)48,300 ± 38,80082,600 ± 77,000a77,400 ± 69,000a107,000 ± 102,000a23,000
SCr values per admit day0.64 ± 0.280.73 ± 0.28a0.73 ± 0.28a0.76 ± 0.25a0.89
Patients who received at least one medication (%)299 (83.8%)316 (88.5%)254 (87.3%)61 (93.8%)1 (100%)
Medication exposure (median and range)2 (0 to 7)2 (0 to 8)a2 (0 to 7)3 (0 to 8)a1
Medication exposure intensity (median and range)2 (0 to 6)2 (0 to 7)a2 (0 to 6)3 (0 to 7)a1
Days of medication therapy (median and range)6 (0 to 75)11 (0 to 271)a10 (0 to 127)a19 (0 to 271)a2
Medication doses (median and range)12 (0 to 191)25 (0 to 562)a23 (0 to 302)a38 (0 to 562)a8
Doses per therapy day2.1 ± 1.32.1 ± 1.22.4 ± 1.22.2 ± 1.14
Medication doses per admission day3.1 ± 2.93.2 ± 2.73.1 ± 2.73.5 ± 2.62
  • a P < 0.05 compared with patients with no AKI.