Hazard ratios for cardiovascular and all-cause mortality by PA as a log-transformed continuous variable
| Model | Cardiovascular Mortality (n = 37) | All-Cause Mortality (n = 81) | ||
|---|---|---|---|---|
| HR [95% CI] | P | HR [95% CI] | P | |
| 1 | 0.51 [0.39 to 0.67] | <0.001 | 0.58 [0.48 to 0.70] | <0.001 |
| 2 | 0.56 [0.41 to 0.76] | <0.001 | 0.67 [0.54 to 0.83] | <0.001 |
| 3 | 0.58 [0.42 to 0.79] | 0.001 | 0.69 [0.55 to 0.85] | 0.001 |
| 4 | 0.61 [0.44 to 0.84] | 0.003 | 0.70 [0.57 to 0.88] | 0.002 |
| 5 | 0.58 [0.42 to 0.80] | 0.001 | 0.70 [0.56 to 0.87] | 0.001 |
| 6 | 0.62 [0.45 to 0.85] | 0.003 | 0.76 [0.61 to 0.95] | 0.02 |
| 7 | 0.62 [0.45 to 0.86] | 0.004 | 0.75 [0.60 to 0.94] | 0.01 |
Model 1: Crude model of physical activity as a continuous variable (log-MET-min/day). Model 2: model 1 + adjustment for age and gender. Model 3: model 2 + adjustment for history of cardiovascular events. Model 4: model 3 + adjustment for insulin concentration, systolic BP, waist circumference, triglycerides, smoking, and hsCRP. Model 5: model 3 + adjustment for Framingham risk score factors (BP, LDL-cholesterol, HDL-cholesterol, smoking, presence of diabetes). Model 6: model 5 + adjustment for creatinine clearance and urinary protein excretion. Model 7: model 5 + adjustment for 24-hour urinary creatinine excretion. HR, hazard ratio; CI, confidence interval.