Rejection, graft loss, steroid exposure and metabolic profile comparison
| ESW | CSM | P | |
|---|---|---|---|
| Biopsy proven rejection | 20% (n = 12) | 26% (14) | 0.509 |
| Time to rejection (days) | 63 (14 to 1258) | 205 (6 to 1285) | 0.819 |
| Type of rejection | |||
| acute cellular rejection | 92% (11) | 72% (10) | 0.330 |
| acute antibody mediated rejection | 8% (1) | 28% (4) | 0.330 |
| Graft loss | 7% (4) | 15% (8) | 0.231 |
| Cause for current graft loss | |||
| rejection | 25% (1) | 50% (4) | 0.575 |
| BK nephropathy | 25% (1) | 0 | |
| death with functioning graft | 50% (2) | 50% (4) | 1.00 |
| Cumulative steroid exposure prior to recent Tx (days) | 3834 (3 to 10,105) | 3600 (8 to 12,784) | 0.552 |
| Cause of prior graft loss | |||
| chronic transplant glomerulopathy | 68% (40) | 79% (43) | 0.363 |
| rejection | 17% (10) | 13% (7) | 0.839 |
| glomerulonephritis | 5% (3) | 4% (2) | 0.934 |
| others | 10% (6) | 4% (2) | 0.408 |
| Metabolic Profile | |||
| systolic blood pressure (mmHg) | 128 + 12 | 129 + 17 | 0.792 |
| diastolic blood pressure (mmHg) | 72 + 12 | 74 + 11 | 0.314 |
| serum albumin (gm/dl) | 4 + 0.5 | 3.7 + 0.5 | 0.005 |
| fasting blood glucose (mg/dl) | 104 + 27 | 101 + 30 | 0.741 |
| serum cholesterol (mg/dl) | 154 + 33 | 153 + 34 | 0.866 |
| serum LDL (mg/dl) | 84 + 29 | 80 + 22 | 0.457 |
| post transplant diabetes mellitus | 1.6% (1) | 11% (6) | 0.051 |
| anti lipid therapy | 44% (26) | 70% (38) | 0.007 |
| no. of blood pressure medications | 1.8 + 1 | 2.6 + 1.3 | 0.004 |
| bisphosphonate therapy | 10% (6) | 35% (19) | 0.010 |