Table 3.

Comparative histologic findings in early TMA

C4d+C4d−P
n79
Glomeruli
    total glomeruli (mean)2418
    thrombi - segmental10033.30.01
    thrombi - global28.600.2
    mesangiolysis28.600.2
    double contours42.922.20.6
    neutrophilic glomerulitis10000.0009
    transplant glomerulitis42.900.06
    global glomerulosclerosis71.488.90.55
    segmental glomerulosclerosis022.20.48
    ischemic glomerulopathy85.7660.6
Peritubular capillaries
    peritubular capillaritis - neutrophils10011.10.001
    peritubular capillaritis - mononuclear57.111.10.1
Arterioles
    obliterative arteriolopathy42.977.80.3
    arteriolar thrombi42.944.41
    arteriolar hyalinosis42.977.80.3
Arteries
    endothelialitis57.100.01
    arterial intimal fibrosis42.944.41
Tubules and interstitium
    ATN85.7660.58
    interstitial mononuclear cells85.71000.4
    tubulitis42.944.41
    interstitial hemorrhage42.900.06
    interstitial fibrosis42.955.60.99
    tubular atrophy28.655.60.36
  • The values are the percentages of biopsies with lesions in each group. ATN, acute tubular necrosis.