Table 4.

Associations among copeptin, GFR, and ERBF as markers of disease severity in ADPKD

ModelAdjusted forGFRERBF
Standardized βPStandardized βP
2As 1 + age and gender−0.55<0.001−0.55<0.001
3As 2 + use of diuretics−0.53<0.001−0.54<0.001
  • Independent variable is log copeptin. Dependent variables are GFR and ERBF (both in ml/min per 1.73 m2). A negative standardized β indicates that a high copeptin concentration is associated with a low GFR or ERBF.