Table 2.

Patient and dialysis characteristics

GFR = 0 (ml/min per 1.73 m2)GFR 0 to 1.65 (ml/min per 1.73 m2)GFR 1.66 to 4.13 (ml/min per 1.73 m2)GFR > 4.13 (ml/min per 1.73 m2)All PatientsPa
n270949494552
Gender (% male)61636756620.51
Age (years)62.3 ± 1464.4 ± 1664.8 ± 1366.2 ± 1263.8 ± 140.08
History of cardiovascular disease (%)42394551430.34
Diabetes mellitus (%)19282727230.17
Body mass index (kg/m2)24.9 ± 4.225.7 ± 5.424.7 ± 4.126.4 ± 5.125.2 ± 4.90.02
Dialysis vintage (years)3.1 (1.5 to 5.4)1.8 (0.8 to 3.1)1.5 (0.83 to 2.5)1.0 (0.7 to 2.1)2.0 (1.0 to 4.0)<0.001
Treatment time (h/wk)12 (10.5 to 12)12 (10.5 to 12)10.9 (10.5 to 12)10.5 (9 to 12)12 (10.5 to 12)<0.001
Kt/V–dialysis (per week)4.23 ± 0.664.07 ± 0.544.07 ± 0.823.64 ± 0.624.08 ± 0.69<0.001
Kt/V–renal (per week)0.21 ± 0.100.64 ± 0.231.56 ± 0.680.40 ± 0.64<0.001
Kt/V–total (per week)4.23 ± 0.664.28 ± 0.534.70 ± 0.835.21 ± 0.844.48 ± 0.80<0.001
Intradialytic weight loss (L)2.13 ± 0.792.15 ± 0.901.69 ± 0.890.99 ± 0.931.87 ± 0.95<0.001
GFR (ml/min per 1.73 m2)0.87 (0.56 to 1.17)2.64 (2.13 to 3.46)6.19 (4.71 to 7.95)0.24 (0.0 to 2.69)<0.001
Urinary output (L per day)241 (158 to 400)745 (488 to 1000)1245 (916 to 1800)700 (350 to 1150)<0.001
nPNA1.07 ± 0.241.12 ± 0.231.25 ± 0.561.25 ± 0.291.14 ± 0.34<0.001
Phosphate-binding agents (%)85888377840.14
ESA (%)90929289900.94
ACEI or ARB (%)4064496149<0.001
  • A urinary output <100 ml/24 h was defined as GFR = 0 ml/min per 1.73 m2. Patients with a urinary output >100 ml/24 h were divided in tertiles based on GFR. Values expressed as mean ± SD or median (interquartile range) or as percentages.

  • a Between groups ANOVA.