Table 3.

Effects of weight reduction in obese patients on metabolic variables and renal markers

Group Unsuccessful in Weight ReductionGroup Successful in Weight Reduction
Before3 MonthsBefore3 Months
Male/female56/7225/29
Age (years)53.4 ± 1.250.4 ± 2.1
BMI (kg/m2)30.7 ± 0.530.7 ± 0.532.1 ± 0.729.7 ± 0.7a
Waist circumference (cm)99.5 ± 1.399.1 ± 1.2102 ± 1.696.3 ± 2.2a
Systolic blood pressure (mmHg)140 ± 1.5137 ± 1.4137 ± 2.7130 ± 2.1a
Diastolic blood pressure (mmHg)81.2 ± 1.180.7 ± 1.081.4 ± 2.576.3 ± 1.3
Fasting plasma glucose (mg/dl)135 ± 4.4134 ± 4.3142 ± 7.6129 ± 7.3b
HbA1c (%)6.85 ± 0.16.83 ± 0.16.98 ± 0.26.45 ± 0.2a
IRI (mU/ml)18.2 ± 1.820.2 ± 2.722.3 ± 5.721.6 ± 10
Triglyceride (mg/dl)162 ± 8.2161 ± 6.8170 ± 12153 ± 12
HDL-C (mg/dl)55.1 ± 1.253.3 ± 1.054.0 ± 1.853.5 ± 1.7
LDL-C (mg/dl)122 ± 3.0123 ± 0.5123 ± 4.3113 ± 3.5a
Leptin (ng/ml)13.9 ± 1.114.6 ± 1.013.6 ± 2.012.2 ± 2.3
Adiponectin (μg/ml)7.11 ± 0.47.73 ± 0.56.76 ± 0.57.98 ± 0.5b
CRP (μg/ml)1.39 ± 0.21.17 ± 0.11.32 ± 0.21.00 ± 0.1
eGFR72.2 ± 2.770.6 ± 2.371.6 ± 3.572.1 ± 3.7
S-CysC (mg/L)0.84 ± 0.030.85 ± 0.030.81 ± 0.040.84 ± 0.05
UACR (mg/g·Cr)116 ± 45132 ± 50158 ± 72130 ± 58
UCCR0.78 ± 0.110.70 ± 0.080.83 ± 0.170.66 ± 0.16a
U-B2MG (μg/L)165 ± 36229 ± 92184 ± 68129 ± 39
U-NAG (U/L)4.70 ± 0.54.02 ± 0.64.08 ± 1.12.96 ± 0.4
CAVI7.92 ± 0.17.89 ± 0.27.75 ± 0.37.42 ± 0.3a
  • The data are expressed as the means ± SEM.

  • a P < 0.01 versus before determined by a two-tailed paired t test.

  • b P < 0.05 versus before determined by a two-tailed paired t test.