Table 1.

Demographic traits of the study sample by polycystic kidney disease diagnosis and kidney function level

Combined Cohort, n (%)aADPKD, ICD9 753.13, n (%)aPolycystic Kidney Unspecified, ICD9 753.12, n (%)a
Full Cohortn = 1913n = 496n = 1417
    Age in years, mean ± SD46.7 ± 12.5b46.8 ± 12.4b46.7 ± 12.5b
    Male gender828 (43.3)b221 (44.6)b607 (42.8)b
    Diabetes102 (5.3)31 (6.3)71 (5.0)
    Cardiovascular disease43 (2.2)b13 (2.6)b30 (2.1)
eGFR ≥90n = 295n = 68n = 227
    Age in years, mean ± SD37.4 ± 12.136.9 ± 11.937.6 ± 12.2
    Male gender94 (31.9)23 (33.8)71 (31.3)
    Diabetes14 (4.8)3 (4.4)11 (4.9)
    Cardiovascular disease3 (1.0)03 (1.3)
eGFR 60 to 89n = 696n = 167n = 529
    Age in years, mean ± SD44.1 ± 11.543.5 ± 11.344.2 ± 11.6
    Male gender272 (39.1)67 (40.1)205 (38.8)
    Diabetes31 (4.5)8 (4.8)23 (4.4)
    Cardiovascular disease5 (0.7)3 (1.8)2 (0.4)
eGFR 30 to 59n = 582n = 158n = 424
    Age in years, mean ± SD51.2 ± 11.050.3 ± 11.051.5 ± 11.0
    Male gender299 (51.4)79 (50.0)220 (51.9)
    Diabetes33 (5.7)15 (9.5)18 (4.3)
    Cardiovascular disease18 (3.1)7 (4.4)11 (2.6)
eGFR 15 to 29n = 205n = 60n = 145
    Age in years, mean ± SD53.1 ± 10.153.4 ± 9.153.0 ± 10.5
    Male gender98 (47.8)34 (56.7)64 (44.1)
    Diabetes13 (6.3)3 (5.0)10 (6.9)
    Cardiovascular disease8 (3.9)1 (1.7)7 (4.8)
eGFR <15n = 135n = 43n = 92
    Age in years, mean ± SD52.1 ± 11.252.7 ± 12.551.8 ± 10.6
    Male gender65 (48.2)18 (41.9)47 (51.1)
    Diabetes11 (8.2)2 (4.6)9 (9.8)
    Cardiovascular disease9 (6.7)2 (4.6)7 (7.6)
  • a Percentages reflect proportions within the polycystic kidney diagnosis code category with the indicated demographic or clinical traits (“column percentages”).

  • There were no statistically significant differences in distributions of listed clinical traits in 753.13 and 743.12 subgroups at the P < 0.05 level.

  • b P < 0.05 for variation in the distribution of clinical traits according to eGFR level within a polycystic kidney diagnosis code category.