Table 5.

Allopurinol effect in inflammatory parameters

hsPCRa (mg/L)C Cystatinb (mg/L)Albuminuria (mg/d)Fibrinogen (mg/dl)
Control group
    Basal3.4 (5.2)2.0 ± 0.732 (383)384 ± 104
    6 months3.0 (7.6)2.0 ± 0.843 (417)373 ± 112
    12 months3.2 (10.8)1.9 ± 1.051 (296)402 ± 98
Allopurinol group
    Basal4.4 (4.5)1.9 ± 0.536 (388)381 ± 78
    6 months3.0 (4.0)c1.8 ± 0.615 (103)367 ± 58
    12 months3.0 (2.5)c1.4 ± 0.416 (166)369 ± 49
  • a P = 0.018 between groups and time periods (two-way ANOVA).

  • b P = 0.008 between groups (two-way ANOVA).

  • c P = 0.04 differences in comparison to baseline period in allopurinol group.

  • Data are expressed as mean ± SD or median (interquartile range). No differences were observed in hemoglobin, ESR, and serum albumin levels between groups and periods.