Table 2.

Main clinical and immunologic features in patients with or without renal involvement

FeaturePatients without Renal Involvement (n = 146)Patients with Renal Involvement (n = 14)P
Age (years; mean ± SD)34.3 ± 11.841.8 ± 12.50.0269
Male/female17/1293/11NS
Follow-up (years; mean ± SD)8.4 ± 6.55.1 ± 4.2NS
Arterial hypertension (%)22.657.10.0122
Thrombotic events (%)41.142.9NS
Fetal loss (%)41.814.3NS
Thrombotic events + fetal loss (%)17.142.9NS
LA positive (%)48.992.30.0068
Anticardiolipin antibodies positive (%)69.985.7NS
Anti–β2-glycoprotein I antibodies (%)75.376.9NS
ANA positive (%)47.964.3NS
Anti-dsDNA positive (%)8.928.6aNS
HypoC3 (%)9.735.70.017
HypoC4 (%)5.242.8<0.001
  • LA, lupus anticoagulant.

  • a Borderline value.