PT  - JOURNAL ARTICLE
AU  - Zhang, Rubin
AU  - Paramesh, Anil
AU  - Florman, Sandy
AU  - Yau, C. Lillian
AU  - Balamuthusamy, Saravanan
AU  - Krane, N. Kevin
AU  - Slakey, Douglas
TI  - Long-Term Outcome of Adults Who Undergo Transplantation with Single Pediatric Kidneys: How Young Is too Young?
AID  - 10.2215/CJN.04610908
DP  - 2009 Sep 01
TA  - Clinical Journal of the American Society of Nephrology
PG  - 1500--1506
VI  - 4
IP  - 9
4099  - http://cjasn.asnjournals.org/content/4/9/1500.short
4100  - http://cjasn.asnjournals.org/content/4/9/1500.full
SO  - CLIN J AM SOC NEPHROL2009 Sep 01; 4
AB  - Background and objectives: The optimal donor age for transplanting a single pediatric kidney in an adult recipient remains unknown. En block kidney transplantation is usually performed when the donor age is <5 yr. Design, setting, participants, & measurements: We compared the outcomes of adult patients who underwent transplantation with single pediatric kidneys from donors who were younger than 5 yr (group 1, n = 40) and from donors who were aged 5 to 10 yr of age (group 2, n = 39) in our center. Results: The donor kidney sizes were significantly smaller in group 1 than in group 2 (P < 0.001), and group 1 required more ureteral stents than group 2 (73 versus 38%). The surgical complications, delayed graft function, and development of proteinuria were similar in both groups. Group 1 had slightly higher rejection episodes than group 2 (25 versus 18%; P = 0.67), and graft function was comparable in both groups. There were no statistical differences between the two groups in patient (P = 0.73) or death-censored graft (P = 0.68) survivals over 5 yr. Conclusions: Single pediatric kidney transplants from donors who are younger than 5 yr can be used with acceptable complications and long-term outcomes as those from older donors.