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Research Letter
Open Access

Humoral Response to Third Dose of SARS-CoV-2 Vaccines in the CKD Spectrum

Borja Quiroga, María José Soler, Alberto Ortiz, Esther Orero, Sandra Tejedor, Carlos Jesús Jarava Mantecón, Virginia Olinda Gómez Pérez, Antonio José Marín Franco, Christian Alfaro Sánchez, Marta Puerta Carretero, María Teresa Jaldo Rodríguez, Manuel Antonio Carnerero Di Riso, Shaira Martínez, Carmen Calderón González, Michal Cervienka, Nicolás Macías Carmona, David Arroyo, Katia M. Pérez del Valle, Gabriel de Arriba, Auxiliadora Mazuecos, Juan Manuel Cazorla, Mónica Pereira, Emilio González Parra, María Gabriela Sánchez Márquez, Carolina Lancho Novillo, Carmen Toyos Ruiz, María Cinta Aguilar Cervera, Patricia Muñoz Ramos, Ana Sánchez Horrillo, Isabel Jimeno Martín, Néstor Toapanta, Secundino Cigarrán Guldris, Montserrat Folgueiras López, Rosalía Valero San Cecilio, Blanca Villacorta Linaza, Ignacio Minguela Pesquera, Raquel Santana Estupiñán, Rocío Zamora, Sagrario Soriano, Eduardo Muñoz de Bustillo, María Soledad Pizarro Sánchez, Ana Isabel Martínez Puerto, Alejandra Yugueros, Laura Muñiz Pacios, Alba Leyva, José Rojas, Ron T. Gansevoort and Patricia de Sequera; on behalf of SENCOVAC collaborative network
CJASN May 2022, CJN.01770222; DOI: https://doi.org/10.2215/CJN.01770222
Borja Quiroga
1Instituto de Investigación Sanitaria-La Princesa, Nephrology Department, Hospital Universitario de la Princesa, Madrid, Spain
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  • ORCID record for Borja Quiroga
María José Soler
2Nephrology Department, Vall d’Hebrón University Hospital, Barcelona, Spain
3Redes de Investigación Cooperativa Orientadas a Resultados en Salud (RICORS), RICORS2040 (Kidney Disease), Spain
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Alberto Ortiz
3Redes de Investigación Cooperativa Orientadas a Resultados en Salud (RICORS), RICORS2040 (Kidney Disease), Spain
4Nephrology Department, Instituto de Investigación Sanitaria-Fundación Jiménez Diaz, School of Medicine, Universidad Autónoma de Madrid, Fundación Renal Iñigo Álvarez de Toledo-IRSIN, Red de Investigación Renal, Instituto de Investigación Carlos III, Madrid, Spain
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Esther Orero
5Dialysis Center, Diaverum, Valencia, Spain
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Sandra Tejedor
5Dialysis Center, Diaverum, Valencia, Spain
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Carlos Jesús Jarava Mantecón
6Dialysis Center, Diaverum, Andalucía, Spain
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Virginia Olinda Gómez Pérez
6Dialysis Center, Diaverum, Andalucía, Spain
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Antonio José Marín Franco
7Dialysis Center, Diaverum , Galicia, Spain
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Christian Alfaro Sánchez
7Dialysis Center, Diaverum , Galicia, Spain
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Marta Puerta Carretero
8Nephrology Department, Hospital Universitario Infanta Leonor–Universidad Complutense de Madrid, Spain
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María Teresa Jaldo Rodríguez
8Nephrology Department, Hospital Universitario Infanta Leonor–Universidad Complutense de Madrid, Spain
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Manuel Antonio Carnerero Di Riso
9Diaverum Murcia-Alicante, Spain
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Shaira Martínez
9Diaverum Murcia-Alicante, Spain
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Carmen Calderón González
10Nephrology Department, Complejo Asistencial de Palencia, Spain
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Michal Cervienka
10Nephrology Department, Complejo Asistencial de Palencia, Spain
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Nicolás Macías Carmona
11Nephrology Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain
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David Arroyo
11Nephrology Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain
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Katia M. Pérez del Valle
12Nephrology Department, Hospital Universitario de Guadalajara, Spain
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Gabriel de Arriba
12Nephrology Department, Hospital Universitario de Guadalajara, Spain
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Auxiliadora Mazuecos
13Nephrology Department, Hospital Universitario Puerta del Mar, Cadiz, Spain
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Juan Manuel Cazorla
13Nephrology Department, Hospital Universitario Puerta del Mar, Cadiz, Spain
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Mónica Pereira
4Nephrology Department, Instituto de Investigación Sanitaria-Fundación Jiménez Diaz, School of Medicine, Universidad Autónoma de Madrid, Fundación Renal Iñigo Álvarez de Toledo-IRSIN, Red de Investigación Renal, Instituto de Investigación Carlos III, Madrid, Spain
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Emilio González Parra
4Nephrology Department, Instituto de Investigación Sanitaria-Fundación Jiménez Diaz, School of Medicine, Universidad Autónoma de Madrid, Fundación Renal Iñigo Álvarez de Toledo-IRSIN, Red de Investigación Renal, Instituto de Investigación Carlos III, Madrid, Spain
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María Gabriela Sánchez Márquez
14Nephrology Department, Hospital Universitario Puerto Real, Cadiz, Spain
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Carolina Lancho Novillo
14Nephrology Department, Hospital Universitario Puerto Real, Cadiz, Spain
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Carmen Toyos Ruiz
15Nephrology Department, Hospital Universitario de Donostia, Spain
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María Cinta Aguilar Cervera
15Nephrology Department, Hospital Universitario de Donostia, Spain
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Patricia Muñoz Ramos
1Instituto de Investigación Sanitaria-La Princesa, Nephrology Department, Hospital Universitario de la Princesa, Madrid, Spain
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Ana Sánchez Horrillo
1Instituto de Investigación Sanitaria-La Princesa, Nephrology Department, Hospital Universitario de la Princesa, Madrid, Spain
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Isabel Jimeno Martín
16Nephrology Department, Hospital Universitario de Galdakao, Vizcaya, Spain
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Néstor Toapanta
2Nephrology Department, Vall d’Hebrón University Hospital, Barcelona, Spain
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Secundino Cigarrán Guldris
17Nephrology Department, Hospital Da Mariña, Lugo, Spain
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Montserrat Folgueiras López
18Nephrology Department, Hospital del Mar, Barcelona, Spain
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Rosalía Valero San Cecilio
19Nephrology Department, Hospital Marqués de Valdecilla, University of Cantabria, Instituto de Investigación Marqués de Valedecilla, Santander, Spain
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Blanca Villacorta Linaza
20Dialysis Unit, Centro Santa Isabel, Sevilla, Spain
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Ignacio Minguela Pesquera
21Nephrology Department, Hospital Universitario Basurto, Bilbao, Spain
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Raquel Santana Estupiñán
22Nephrology Department, Hospital Universitario de Gran Canaria Doctor Negrín, Las Palmas de Gran Canaria, Spain
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Rocío Zamora
23Nephrology Department, Hospital Universitario General de Villalba, Spain
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Sagrario Soriano
24Nephrology Department, Hospital Reina Sofía, Cordoba, Spain
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Eduardo Muñoz de Bustillo
25Nephrology Department, Hospital General de Alicante, Spain
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María Soledad Pizarro Sánchez
26Nephrology Department, Hospital Rey Juan Carlos, Madrid, Spain
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Ana Isabel Martínez Puerto
27Nephrology Department, Hospital Universitario Virgen Macarena, Sevilla, Spain
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Alejandra Yugueros
28Nephrology Department, Hospital Lluis Alcanyis De Xátiva, Valencia, Spain
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Laura Muñiz Pacios
29Nephrology Department, Hospital Universitario Infanta Cristina, Madrid, Spain
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Alba Leyva
30Research and Development Department, Vircell Sociedad Limitada, Granada, Spain
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José Rojas
30Research and Development Department, Vircell Sociedad Limitada, Granada, Spain
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Ron T. Gansevoort
31Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
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Patricia de Sequera
3Redes de Investigación Cooperativa Orientadas a Resultados en Salud (RICORS), RICORS2040 (Kidney Disease), Spain
8Nephrology Department, Hospital Universitario Infanta Leonor–Universidad Complutense de Madrid, Spain
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    Figure 1.

    Anti-Spike antibodies during follow-up in CKD cohorts. (A) Anti-Spike antibodies titers during follow-up in different CKD cohorts. Data show anti-Spike antibodies titers of all patients irrespective of their baseline anti-Spike antibody titers. (B) Presence of anti-Spike antibodies during follow-up in the different CKD cohorts. Data are expressed as the percentage of patients with the presence of anti-Spike antibodies (i.e., titer >36 IU/ml). The table shows the sample size of each CKD group across each time point. Only significant P values are shown. HD, hemodialysis; PD, peritoneal dialysis.

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Clinical Journal of the American Society of Nephrology: 17 (5)
Clinical Journal of the American Society of Nephrology
Vol. 17, Issue 5
May 2022
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Humoral Response to Third Dose of SARS-CoV-2 Vaccines in the CKD Spectrum
Borja Quiroga, María José Soler, Alberto Ortiz, Esther Orero, Sandra Tejedor, Carlos Jesús Jarava Mantecón, Virginia Olinda Gómez Pérez, Antonio José Marín Franco, Christian Alfaro Sánchez, Marta Puerta Carretero, María Teresa Jaldo Rodríguez, Manuel Antonio Carnerero Di Riso, Shaira Martínez, Carmen Calderón González, Michal Cervienka, Nicolás Macías Carmona, David Arroyo, Katia M. Pérez del Valle, Gabriel de Arriba, Auxiliadora Mazuecos, Juan Manuel Cazorla, Mónica Pereira, Emilio González Parra, María Gabriela Sánchez Márquez, Carolina Lancho Novillo, Carmen Toyos Ruiz, María Cinta Aguilar Cervera, Patricia Muñoz Ramos, Ana Sánchez Horrillo, Isabel Jimeno Martín, Néstor Toapanta, Secundino Cigarrán Guldris, Montserrat Folgueiras López, Rosalía Valero San Cecilio, Blanca Villacorta Linaza, Ignacio Minguela Pesquera, Raquel Santana Estupiñán, Rocío Zamora, Sagrario Soriano, Eduardo Muñoz de Bustillo, María Soledad Pizarro Sánchez, Ana Isabel Martínez Puerto, Alejandra Yugueros, Laura Muñiz Pacios, Alba Leyva, José Rojas, Ron T. Gansevoort, Patricia de Sequera
CJASN May 2022, CJN.01770222; DOI: 10.2215/CJN.01770222

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Humoral Response to Third Dose of SARS-CoV-2 Vaccines in the CKD Spectrum
Borja Quiroga, María José Soler, Alberto Ortiz, Esther Orero, Sandra Tejedor, Carlos Jesús Jarava Mantecón, Virginia Olinda Gómez Pérez, Antonio José Marín Franco, Christian Alfaro Sánchez, Marta Puerta Carretero, María Teresa Jaldo Rodríguez, Manuel Antonio Carnerero Di Riso, Shaira Martínez, Carmen Calderón González, Michal Cervienka, Nicolás Macías Carmona, David Arroyo, Katia M. Pérez del Valle, Gabriel de Arriba, Auxiliadora Mazuecos, Juan Manuel Cazorla, Mónica Pereira, Emilio González Parra, María Gabriela Sánchez Márquez, Carolina Lancho Novillo, Carmen Toyos Ruiz, María Cinta Aguilar Cervera, Patricia Muñoz Ramos, Ana Sánchez Horrillo, Isabel Jimeno Martín, Néstor Toapanta, Secundino Cigarrán Guldris, Montserrat Folgueiras López, Rosalía Valero San Cecilio, Blanca Villacorta Linaza, Ignacio Minguela Pesquera, Raquel Santana Estupiñán, Rocío Zamora, Sagrario Soriano, Eduardo Muñoz de Bustillo, María Soledad Pizarro Sánchez, Ana Isabel Martínez Puerto, Alejandra Yugueros, Laura Muñiz Pacios, Alba Leyva, José Rojas, Ron T. Gansevoort, Patricia de Sequera
CJASN May 2022, CJN.01770222; DOI: 10.2215/CJN.01770222
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Keywords

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