Original ArticlesESRD and Chronic Dialysis

Cumulative Patency of Contemporary Fistulas versus Grafts (2000–2010)

Charmaine E. Lok, Jessica M. Sontrop, George Tomlinson, Dheeraj Rajan, Mark Cattral, George Oreopoulos, Jeremy Harris and Louise Moist
CJASN May 2013, 8 (5) 810-818; DOI: https://doi.org/10.2215/CJN.00730112

Article Figures & Data

Figures

  • Figure 1.
    Figure 1.

    Survival curves of cumulative patency in hemodialysis patients. (A) 1140 patients: arteriovenous fistulas versus arteriovenous grafts (hazard ratio [HR], 0.99; 95% confidence interval [CI], 0.79–1.23). (B) 714 patients after excluding 426 primary failures: arteriovenous fistulas versus arteriovenous grafts (HR, 0.56; 95% CI, 0.43–0.74).

  • Figure 2.
    Figure 2.

    Survival curves of cumulative patency in hemodialysis patients with forearm access. (A) 697 patients: arteriovenous fistulas versus arteriovenous grafts (hazard ratio [HR], 0.96; 95% confidence interval [CI], 0.74−1.24; P = 0.64). (B) 425 patients after excluding 272 primary failures: arteriovenous fistulas versus arteriovenous grafts (HR, 0.47; 95% CI, 0.34−0.66; P < 0.001).

  • Figure 3.
    Figure 3.

    Survival curves of cumulative patency in hemodialysis patients with upper-arm access. (A) 443 patients: arteriovenous fistulas versus arteriovenous grafts (hazard ratio [HR], 1.22; 95% confidence interval [CI], 0.77−1.90; P = 0.37). (B) 289 patients after excluding 154 primary failures: arteriovenous fistulas versus arteriovenous grafts (HR, 0.94; 95% CI, 0.53−1.67; P=0.83).

Tables

  • Table 1.

    Patient characteristics at time of first access creation in 1140 hemodialysis patients

    CharacteristicOverall (n=1140)Dialysis AccessP Valuea
    AV Fistula (n=1012)AV Graft (n=128)
    Mean age (yr)60.0 (18–91)b59.8 (16.4)61.3 (14.9)0.34
    Age ≥ 65 yr513 (45.0)453 (44.8)60 (46.9)0.65
    Male734 (64.4)682 (67.4)52 (40.6)<0.001
    Race
     White823 (72.2)741 (73.2)82 (64.1)0.03
     Black70 (6.1)55 (5.4)16 (12.5)0.002
     Other244 (21.5)214 (21.2)30 (23.4)0.90
    Mean body mass index (kg/m2)27.0 (6.6)26.5 (6.2)30.4 (8.0)<0.0001
    Primary renal diagnosis
     Hypertension230 (20.2)214 (21.1)16 (12.5)0.02
     Diabetes333 (29.2)280 (27.7)53 (41.4)0.001
     GN169 (14.8)151 (14.9)18 (14.1)0.80
     Interstitial nephritis19 (1.7)16 (1.6)3 (2.3)0.53
     Hereditary/other308 (27.0)277 (27.4)31 (24.2)
     Unknown81 (7.1)74 (7.3)7 (5.5)0.44
    Median duration of dialysis at time of access creation (mo) (IQR)0.92 (−3.39 to 5.85)0.92 (−3.68 to 5.56)1.51 (−1.05 to 7.40)0.62
    Comorbid conditions
     Diabetes463 (40.6)390 (38.5)73 (57.0)<0.0001
     Hypertension825 (72.4)727 (71.8)98 (76.6)0.26
     Coronary artery disease274 (24.0)237 (23.4)37 (28.9)0.17
     Congestive heart failure148 (13.0)123 (12.1)25 (19.5)0.02
     Peripheral vascular disease90 (7.9)79 (7.8)11 (8.6)0.76
     Cerebrovascular disease107 (9.4)92 (9.0)15 (11.7)0.33

    • Unless otherwise noted, values are numbers (percentages). Means are given with SDs. AV, arteriovenous; IQR, interquartile range.

    • ↵a Variables were compared using the chi-squared test or t test as appropriate.

    • ↵b Range.

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Cumulative Patency of Contemporary Fistulas versus Grafts (2000–2010)
Charmaine E. Lok, Jessica M. Sontrop, George Tomlinson, Dheeraj Rajan, Mark Cattral, George Oreopoulos, Jeremy Harris, Louise Moist
CJASN May 2013, 8 (5) 810-818; DOI: 10.2215/CJN.00730112
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