Article Figures & Data
Figures
- Figure 1.
Kaplan–Meier survival curves in dialyzed ESRD patients with granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), and other causes of ESRD in Australian and New Zealand during 1996–2010.
- Figure 2.
Kaplan–Meier first graft survival curves in transplanted ESRD patients with granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), and other causes of ESRD in Australia and New Zealand during 1996–2010.
- Figure 3.
Kaplan–Meier patient survival curves in transplanted ESRD patients with granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), and other causes of ESRD in Australia and New Zealand during 1996–2010.
Tables
- Table 1.
Characteristics of all patients with ESRD secondary to granulomatosis with polyangiitis and microscopic polyangiitis or other causes in Australia and New Zealand during 1996–2010
Characteristic Granulomatosis with Polyangiitis (n=221) Microscopic Polyangiitis (n=228) Other ESRD (n=36,435) P Value Age (yr) 60.7±16.4 61.8±15.4 58.0±16.7 <0.001 Age category (yr) 0.05 0–9 0 (0) 1 (0) 312 (1) 10–19 5 (2) 4 (2) 584 (2) 20–29 9 (4) 7 (3) 1570 (4) 30–39 12 (5) 9 (4) 2800 (8) 40–49 24 (11) 22 (10) 4921 (14) 50–59 39 (18) 38 (17) 7239 (20) 60–69 54 (24) 64 (28) 8565 (24) 70–79 63 (29) 69 (30) 8212 (23) ≥80 15 (7) 14 (6) 2232 (6.1) Male 153 (61.1) 153 (67.1) 21,677 (59.5) 0.06 Racial origin <0.001 European 209 (95) 214 (94) 26,746 (73) ATSI 0 (0) 2 (1) 2736 (8) MPI 4 (2) 3 (1) 3784 (10) Asian 6 (3) 4 (2) 1824 (5) Other 2 (1) 5 (2) 1345 (4) RRT era 0.23 1996–2000 60 (27) 71 (31) 9730 (27) 2001–2005 85 (39) 75 (33) 12,241 (34) 2006–2010 76 (34) 82 (36) 14,464 (40) Ever smoked 0.13 Current 19 (9) 34 (15) 4747 (13) Former 88 (40) 104 (46) 14,409 (40) Never 114 (52) 90 (40) 17,271 (47) Missing 0 (0) 0 (0) 8 (0) Hypertension <0.001 Yes 104 (47) 112 (49) 17,670 (48) No 31 (14) 27 (12) 2720 (8) Missing 86 (39) 89 (39) 16,045 (44) Diabetes mellitus <0.001 Yes 34 (15) 33 (14) 14,771 (41) No 187 (85) 195 (86) 21,664 (59) Chronic lung disease <0.001 Yes 59 (27) 54 (24) 5746 (16) No 162 (73) 174 (76) 30,689 (84) Coronary artery disease <0.001 Yes 61 (28) 64 (28) 14,242 (39) No 160 (72) 164 (72) 22,192 (61) Missing 0 (0) 0 (0) 1 (0) Peripheral vascular disease <0.001 Yes 39 (18) 29 (13) 9336 (26) No 182 (82) 199 (87) 27,098 (74) Missing 0 (0) 0 (0) 1 (0) Cerebrovascular disease 0.03 Yes 18 (8) 24 (10) 5402 (15) No 203 (92) 204 (90) 31,032 (85) Missing 0 (0) 0 (0) 1 (0) BMI (kg/m2) 25.8±5.3 25.5±5.2 27.1±6.4 <0.001 First RRT <0.001 Hemodialysis 186 (84) 181 (79) 25,626 (70) Peritoneal dialysis 33 (15) 43 (19) 9627 (26) Renal transplant 2 (1) 4 (2) 1182 (3) Renal biopsy <0.001 Yes 210 (95) 219 (96) 11,198 (31) No 10 (5) 8 (4) 24,397 (67) Missing 1 (0) 1 (0) 840 (2) Follow-up (years) 3.0 (1.0–5.8) 3.3 (1.3–5.7) 3.1 (1.3–5.9) 0.08 Data are presented as mean ± SD, n (%), or median (range). ATSI, Aboriginal and Torres Strait Islander; MPI, Maori and Pacific Islander; RRT, renal replacement therapy; BMI, body mass index.
- Table 2.
Characteristics of all renal transplant patients with ESRD secondary to ANCA-associated vasculitis or other causes in Australia and New Zealand during the period 1996–2010
Characteristic Granulomatosis with Polyangiitis (n=47) Microscopic Polyangiitis (n=46) Other ESRD (n=8193) P Value Age (yr) 46.5±14.5 52.8±15.8 44.1±15.4 <0.001 Male 33 (70) 28 (61) 5076 (62) 0.50 Racial origin 0.08 European 45 (96) 44 (96) 6722 (82) ATSI 0 (0) 0 (0) 241 (3) MPI 0 (0) 0 (0) 341 (4) Asian 2 (4) 0 (0) 524 (6) Other 0 (0) 2 (4) 365 (5) Transplant era 0.41 1996–2000 15 (32) 17 (37) 1543 (19) 2001–2005 24 (51) 18 (39) 2937 (36) 2006–2010 8 (17) 11 (24) 3713 (45) Ever smoked 0.56 Current 3 (6) 7 (15) 873 (11) Former 14 (30) 18 (39) 2423 (30) Never 30 (64) 21 (46) 4890 (60) Missing 0 (0) 0 (0) 7 (0) Hypertension 0.64 Yes 27 (57) 29 (63) 4879 (60) No 8 (17) 4 (9) 859 (10) Missing 12 (26) 13 (28) 2455 (30) Diabetes mellitus 0.04 Yes 3 (6) 3 (7) 1323 (16) No 44 (94) 43 (94) 6870 (84) Chronic lung disease <0.001 Yes 6 (13) 9 (20) 352 (4) No 41 (87) 37 (80) 7841 (96) Coronary artery disease 0.57 Yes 6 (13) 3 (7) 749 (9) No 41 (87) 43 (94) 7444 (91) Peripheral vascular disease 0.19 Yes 5 (11) 1 (2) 458 (6) No 42 (89) 45 (98) 7735 (94) Cerebrovascular disease 0.40 Yes 3 (6) 2 (4) 256 (3) No 44 (94) 44 (96) 7937 (97) BMI (kg/m2) 24.9±4.0 26.1±4.6 25.3±5.2 0.68 Late referral <0.001 Yes 13 (28) 18 (39) 1338 (16) No 34 (72) 28 (61) 6808 (83) Missing 0 (0) 0 (0) 47 (1) Donor type 0.76 Deceased 28 (57) 25 (51) 4748 (56) Living 2 (43) 24 (49) 3694 (44) Subsequent grafts 0.76 Second 2 (1) 3 (1) 254 (3) Third 0 (0) 0 (0) 6 (0) Data are presented as mean ± SD, n (%), or median (range). ATSI, Aboriginal and Torres Strait Islander; MPI, Maori and Pacific Islander; BMI, body mass index; RRT, renal replacement therapy.
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