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Dialysis
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Hydration Status Does Not Influence Peritoneal Equilibration Test Ultrafiltration Volumes

Andrew Davenport and Michelle Kay Willicombe
CJASN July 2009, 4 (7) 1207-1212; DOI: https://doi.org/10.2215/CJN.01060209
Andrew Davenport
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Michelle Kay Willicombe
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  • Figure 1.
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    Figure 1.

    There was a positive correlation between the net PET ultrafiltrate volume and the 24-h net peritoneal dialysate ultrafiltrate corrected for body surface area (1.73 m2).

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    Figure 2.

    Bland–Altman plot of the difference between the net PET and 24-h peritoneal dialysate volumes corrected for body surface area (1.73 m2) and compared with the mean of the sum of values.

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    Figure 3.

    There was a positive correlation between the PET 4-h dialysate to plasma creatinine (D/PCr) and the 4-h PET dialysate to plasma sodium (D/PNa) ratio.

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    Figure 4.

    There was no correlation between the 4-h dialysate to plasma sodium (D4/PNa) and the 24-h net peritoneal dialysate ultrafiltrate corrected for body surface area (1.73 m2). r = 0.09, P = 0.18.

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    Table 1.

    Patient demographicsa

    DemographicValueRange
    Age (yr)54.5 ± 16.017 to 89
    Gender47.4% male
    Weight (kg)70.1 ± 15.542.5 to 122.7
    Months on peritoneal dialysis29.9 ± 29.61 to 203
    Urine output (ml/d)941 ± 7340 to 2925
    Systolic BP (mmHg)138 ± 27.463 to 219
    Diastolic BP (mmHg)81.3 ± 15.643 to 137
    Weekly peritoneal Kt/V1.47 ± 0.610.34 to 3.6
    Total weekly Kt/V2.61 ± 1.061.32 to 11.1
    Intracellular water l21.4 ± 5.412 to 37.4
    Extracellular water l13.7 ± 3.47.8 to 24.3
    ECW/ht l/m8.29 ± 1.585.2 to 12.9
    ECW/1.73m210.1 ± 0.614.5 to 14.0
    ECW/TBW0.39 ± 0.010.366 to 0.43
    Albumin (g/L)38.7 ± 4.321 to 50
    CRP (g/L)9.1 ± 2.30.1 to 233
    Glucose (mmol/L)6.59 ± 4.31.1 to 34
    HbA1c (%)6.06 ± 1.323.7 to 11.0
    Sodium (mmol/L)137.6 ± 4.6121 to 150
    D4/P creatinine0.72 ± 0.130.32 to 1.06
    D4/P sodium0.929 ± 0.0390.814 to 1.02
    D4/D0 glucose0.33 ± 0.070.08 to 0.59
    Sodium removed (mmol)36.2 ± 26.6−40 to 128.
    Net ultrafiltrate (ml)281.3 ± 212.6−300 to 1000
    Net ultrafiltrate (ml/1.73 m2)358.1 ± 55.4−319 to 397
    • ↵a Extracellular water adjusted for height (ECW/ht), and ratio to total body water (ECW/TBW). BP, blood pressure; CRP, C-reactive protein; D4-h/P sodium, 4-h PET dialysate to plasma sodium ratio; D4/P creatinine, 4-h PET dialysate to plasma creatinine; D4/D0 glucose, 4-h PET dialysate glucose to initial dialysate.

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    Table 2.

    Factors associated with peritoneal equilibration test (PET) ultrafiltration volumesa

    Factorr ValueP Value
    Sodium in ultrafiltrate0.9972<0.0001
    D4-h/P sodium−0.25750.0002
    24-h peritoneal dialysis ultrafiltration0.23990.0005
    D4/D0 glucose0.23130.0008
    Serum albumin−0.21280.0020
    D4/P creatinine−0.19660.0043
    D2/P sodium−0.16080.0206
    Serum sodium−0.15130.0292
    • ↵a Dialysate (D) and plasma (P) values. Extracellular water (ECW) and total body water (TBW) were corrected to 1.73 m2. The sodium in the ultrafiltrate was the difference between the sodium instilled and that recovered at the end of the PET.

      D4-h/P sodium, 4-h PET dialysate to plasma sodium ratio; D4/P creatinine, 4-h PET dialysate to plasma creatinine; D4/D0 glucose, 4-h PET dialysate glucose to initial dialysate.

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    Table 3.

    Factors associated with PET ultrafiltration volumesa

    VariableF ValueP Value
    Serum albumin13.380.000
    Serum sodium10.0650.001
    Net sodium removed>500.000
    D4/P sodium14.0530.000
    24-h peritoneal ultrafiltrate15.5160.000
    • ↵a Multiple linear logistical regression model. Net sodium removed refers to the PET test. D4/P sodium, 4-h PET dialysate to plasma sodium ratio.

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Clinical Journal of the American Society of Nephrology
Vol. 4, Issue 7
July 2009
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Hydration Status Does Not Influence Peritoneal Equilibration Test Ultrafiltration Volumes
Andrew Davenport, Michelle Kay Willicombe
CJASN Jul 2009, 4 (7) 1207-1212; DOI: 10.2215/CJN.01060209

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Hydration Status Does Not Influence Peritoneal Equilibration Test Ultrafiltration Volumes
Andrew Davenport, Michelle Kay Willicombe
CJASN Jul 2009, 4 (7) 1207-1212; DOI: 10.2215/CJN.01060209
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