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Dialysis
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Predictors of Peritonitis in Patients on Peritoneal Dialysis: Results of a Large, Prospective Canadian Database

Sharon J. Nessim, Joanne M. Bargman, Peter C. Austin, Rosane Nisenbaum and Sarbjit V. Jassal
CJASN July 2009, 4 (7) 1195-1200; DOI: https://doi.org/10.2215/CJN.00910209
Sharon J. Nessim
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Joanne M. Bargman
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Peter C. Austin
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Rosane Nisenbaum
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Sarbjit V. Jassal
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    Table 1.

    Patient demographics (n = 4247)a

    ParameterValue
    Age (yr; mean ± SD)59 ± 16
    Male gender (%)55
    Race (%)
        White82
        Black2
        Asian6
        Other10
    Modality (% on CAPD)
        initial74
        most recent52
    Modality before PD start (%)
        new to dialysis58
        transfer from HD24
        failed transplant3
        other/unknown15
    Cause of ESRD
        diabetes35
        hypertension17
        glomerulonephritis15
        cystic kidney disease5
        other27
    Diabetes40
    • ↵a CAPD, continuous ambulatory peritoneal dialysis; PD, peritoneal dialysis; HD, hemodialysis.

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    Table 2.

    Multivariable regression models (n = 2555 episodes in 4247 patients)a

    ParameterNegative Binomial ModelAndersen-Gill Model
    RR95% CIPHR95% CIP
    Age (per decade)1.041.01 to 1.080.0101.031.01 to 1.060.025
    Black1.371.00 to 1.880.0501.471.15 to 1.880.002
    Asian0.890.74 to 1.080.2400.910.78 to 1.060.230
    Diabetes
        female1.271.10 to 1.470.0011.311.17 to 1.48<0.001
        male0.990.87 to 1.130.8801.020.91 to 1.140.750
    GN0.870.75 to 1.000.0500.860.76 to 0.970.015
    Transfer from HD1.241.11 to 1.38<0.0011.241.13 to 1.35<0.001
    Failed transplant1.270.95 to 1.690.1201.180.93 to 1.490.170
    CAPD versusAPDb1.030.91 to 1.160.6501.020.92 to 1.130.690
    • ↵a APD, automated PD; CI, confidence interval; GN, glomerulonephritis; HR, hazard ratio; RR, rate ratio.

    • ↵b Subgroup of 3180 patients who did not switch between CAPD and APD during their time on PD.

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    Table 3.

    Comparison of peritonitis rates for several organism categories among subgroups of patients with higher overall peritonitis ratesa

    ParameterFemale Patients with DiabetesTransfer from HDBlack
    RR95% CIPRR95% CIPRR95% CIP
    Gram positive1.331.09 to 1.620.0051.261.08 to 1.460.0031.721.15 to 2.560.010
    Gram negative1.040.77 to 1.400.7801.120.89 to 1.420.3501.390.73 to 2.640.320
    Culture negative1.371.04 to 1.810.0271.190.96 to 1.490.1200.700.31 to 1.570.390
    CNS1.250.95 to 1.630.1101.331.09 to 1.620.0051.410.80 to 2.470.240
    Staphylococcus aureus1.160.69 to 1.940.5801.130.76 to 1.670.5400.570.13 to 2.610.470
    Streptococcus1.571.06 to 2.320.0261.160.84 to 1.600.3702.751.35 to 5.590.005
    • ↵a CNS, coagulase-negative Staphylococcus.

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Clinical Journal of the American Society of Nephrology
Vol. 4, Issue 7
July 2009
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Predictors of Peritonitis in Patients on Peritoneal Dialysis: Results of a Large, Prospective Canadian Database
Sharon J. Nessim, Joanne M. Bargman, Peter C. Austin, Rosane Nisenbaum, Sarbjit V. Jassal
CJASN Jul 2009, 4 (7) 1195-1200; DOI: 10.2215/CJN.00910209

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Predictors of Peritonitis in Patients on Peritoneal Dialysis: Results of a Large, Prospective Canadian Database
Sharon J. Nessim, Joanne M. Bargman, Peter C. Austin, Rosane Nisenbaum, Sarbjit V. Jassal
CJASN Jul 2009, 4 (7) 1195-1200; DOI: 10.2215/CJN.00910209
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More in this TOC Section

  • Cardiac Geometry in Children Receiving Chronic Peritoneal Dialysis: Findings from the International Pediatric Peritoneal Dialysis Network (IPPN) Registry
  • Geographic and Educational Factors and Risk of the First Peritonitis Episode in Brazilian Peritoneal Dialysis Study (BRAZPD) Patients
  • Defining Left Ventricular Hypertrophy in Children on Peritoneal Dialysis
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  • Simultaneous Removal And Reinsertion of the PD Catheter in Relapsing Peritonitis
  • The Effect of Automated Versus Continuous Ambulatory Peritoneal Dialysis on Mortality Risk In China
  • Racial Differences in Home Dialysis Utilization and Outcomes in Canada
  • Representativeness of Honeypot Trial Participants to Australasian PD Patients
  • Center-Centered in a Patient-Centered World?
  • Center-Specific Factors Associated with Peritonitis Risk--A Multi-Center Registry Analysis
  • Identification of Targets for Prevention of Peritoneal Catheter Tunnel and Exit-Site Infections in Low Incidence Settings
  • The Impact of Transfer from Hemodialysis on Peritoneal Dialysis Technique Survival
  • Correlation Between Glycemic Control and the Incidence of Peritoneal and Catheter Tunnel and Exit-Site Infections in Diabetic Patients Undergoing Peritoneal Dialysis
  • The Negative Impact of Early Peritonitis on Continuous Ambulatory Peritoneal Dialysis Patients
  • The Association between Peritoneal Dialysis Modality and Peritonitis
  • Predictors of Peritonitis, Hospital Days, and Technique Survival for Peritoneal Dialysis Patients in a Managed Care Setting
  • 32 Years' Experience of Peritoneal Dialysis-Related Peritonitis in a University Hospital
  • Predictors of Peritonitis and the Impact of Peritonitis on Clinical Outcomes of Continuous Ambulatory Peritoneal Dialysis Patients in Taiwan--10 Years' Experience in a Single Center
  • Is Female Sex Really a Risk Factor for Infectious Death in Peritoneal Dialysis?
  • Determinants of Peritoneal Dialysis Technique Failure in Incident US Patients
  • Old and New Perspectives on Peritoneal Dialysis in Italy Emerging from the Peritoneal Dialysis Study Group Census
  • Getting Excited about Exit Sites in Peritoneal Dialysis?
  • Microbiology of Peritonitis in Peritoneal Dialysis Patients with Multiple Episodes
  • Does Allograft Failure Impact Infection Risk on Peritoneal Dialysis: A North American Pediatric Renal Trials and Collaborative Studies Study
  • High Rates of Mortality and Technique Failure in Peritoneal Dialysis Patients After Critical Illness
  • ISPD Position Statement on Reducing the Risks of Peritoneal Dialysis-Related Infections
  • Microbiology and Outcomes of Peritonitis in Australian Peritoneal Dialysis Patients
  • Peritoneal Dialysis-Associated Peritonitis Rates and Outcomes in a National Cohort Are Not Improving in the Post-Millennium (2000 - 2007)
  • Geographic and Educational Factors and Risk of the First Peritonitis Episode in Brazilian Peritoneal Dialysis Study (BRAZPD) Patients
  • Peritonitis and Exit Site Infections in First Nations Patients on Peritoneal Dialysis
  • Adverse outcomes among Aboriginal patients receiving peritoneal dialysis
  • Survival of Patients With Type 1 Diabetes Receiving Renal Replacement Therapy in 1980-2007
  • Strategies for Improving Long-Term Survival in Peritoneal Dialysis Patients
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