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Dialysis
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A Standard, Noninvasive Monitoring of Hematocrit Algorithm Improves Blood Pressure Control in Pediatric Hemodialysis Patients

Hiren P. Patel, Stuart L. Goldstein, John D. Mahan, Beth Smith, Cheryl B. Fried, Helen Currier and Joseph T. Flynn
CJASN March 2007, 2 (2) 252-257; DOI: https://doi.org/10.2215/CJN.02410706
Hiren P. Patel
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Stuart L. Goldstein
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John D. Mahan
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Beth Smith
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Cheryl B. Fried
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Helen Currier
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Joseph T. Flynn
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    Figure 1.

    Change in casual BP during the 6-mo study period. Month 0 represents the baseline period. Mean BP index represents the mean over the last week of the respective study month. DBP, diastolic BP; HD, hemodialysis; SBP, systolic BP.

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    Figure 2.

    Effect of noninvasive monitoring (NIVM) algorithm on ambulatory BP monitoring (ABPM) profile. (A) Daytime SBP index. (B) Daytime DBP index. (C) Nighttime SBP index. (D) Nighttime DBP index. All BP were indexed to ABPM 95th percentile values for gender and height (24).

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    Table 1.

    Effect of NIVM algorithm on outcome parametersa

    Outcome VariableBaselineEnd of StudyPb
    Estimated dry weight (kg)48.84 ± 16.8348.78 ± 15.92NS
    Pre-HD weight (kg)51.69 ± 18.7452.11 ± 16.65NS
    Post-HD weight (kg)49.25 ± 17.1449.24 ± 15.62NS
    Casual pre-HD SBP index0.99 ± 0.160.93 ± 0.120.08
    Casual pre-HD DBP index0.85 ± 0.240.79 ± 0.19NS
    Casual post-HD SBP index0.93 ± 0.130.86 ± 0.110.04
    Casual post-HD DBP index0.76 ± 0.220.69 ± 0.150.08
    LVMI (g/m2.7; n = 11)41.6 ± 16.941.2 ± 14.3NS
    • ↵a DBP, diastolic BP; HD, hemodialysis; LVMI, left ventricular mass index; NIVM, noninvasive monitoring of hematocrit; SBP, systolic BP. BP index equals measured BP divided by the 95th percentile value.

    • ↵b P > 0.10 is reported as NS.

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    Table 2.

    Number of antihypertensive medications prescribed by category for all patients who completed the study (n = 16)

    Antihypertensive Medication CategoryBaselineEnd of Study
    ACEI/ARBa74
    Calcium channel blocker63
    β blocker31
    Central α agonist (clonidine)32
    Total1910
    • ↵a ACEI, angiotensin-converting enzyme inhibitors; ARB, angiotensin receptor blocker.

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Clinical Journal of the American Society of Nephrology
Vol. 2, Issue 2
March 2007
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A Standard, Noninvasive Monitoring of Hematocrit Algorithm Improves Blood Pressure Control in Pediatric Hemodialysis Patients
Hiren P. Patel, Stuart L. Goldstein, John D. Mahan, Beth Smith, Cheryl B. Fried, Helen Currier, Joseph T. Flynn
CJASN Mar 2007, 2 (2) 252-257; DOI: 10.2215/CJN.02410706

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A Standard, Noninvasive Monitoring of Hematocrit Algorithm Improves Blood Pressure Control in Pediatric Hemodialysis Patients
Hiren P. Patel, Stuart L. Goldstein, John D. Mahan, Beth Smith, Cheryl B. Fried, Helen Currier, Joseph T. Flynn
CJASN Mar 2007, 2 (2) 252-257; DOI: 10.2215/CJN.02410706
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More in this TOC Section

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  • Defining Left Ventricular Hypertrophy in Children on Peritoneal Dialysis
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