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Original ArticleGenetics
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APOL1 Kidney Risk Variants and Proteomics

Teresa K. Chen, Aditya L. Surapaneni, Dan E. Arking, Christie M. Ballantyne, Eric Boerwinkle, Jingsha Chen, Josef Coresh, Anna Köttgen, Katalin Susztak, Adrienne Tin, Bing Yu and Morgan E. Grams
CJASN May 2022, 17 (5) 684-692; DOI: https://doi.org/10.2215/CJN.14701121
Teresa K. Chen
1Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland
2Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, Maryland
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Aditya L. Surapaneni
2Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, Maryland
3Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland
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Dan E. Arking
4McKusick-Nathans Institute, Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland
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Christie M. Ballantyne
5Department of Medicine, Baylor College of Medicine, Houston, Texas
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Eric Boerwinkle
6Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas
7Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas
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Jingsha Chen
3Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland
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Josef Coresh
1Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland
2Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, Maryland
3Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland
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  • ORCID record for Josef Coresh
Anna Köttgen
3Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland
8Department of Data Driven Medicine, Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany
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Katalin Susztak
9Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania
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Adrienne Tin
10Department of Medicine, The University of Mississippi Medical Center, Jackson, Mississippi
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Bing Yu
6Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas
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Morgan E. Grams
3Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland
11Department of Medicine, New York University Langone School of Medicine, New York, New York
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Article Information

vol. 17 no. 5 684-692
DOI 
https://doi.org/10.2215/CJN.14701121
PubMed 
35474272

Published By 
American Society of Nephrology
Print ISSN 
1555-9041
Online ISSN 
1555-905X
History 
  • Received November 11, 2021
  • Accepted March 17, 2022
  • Published online May 6, 2022.

Article Versions

  • Earlier version (April 26, 2022 - 08:36).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2022 by the American Society of Nephrology

Author Information

  1. Teresa K. Chen1,2,
  2. Aditya L. Surapaneni2,3,
  3. Dan E. Arking4,
  4. Christie M. Ballantyne5,
  5. Eric Boerwinkle6,7,
  6. Jingsha Chen3,
  7. Josef Coresh1,2,3,
  8. Anna Köttgen3,8,
  9. Katalin Susztak9,
  10. Adrienne Tin10,
  11. Bing Yu6,
  12. Morgan E. Grams3,11
  1. 1Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland
  2. 2Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, Maryland
  3. 3Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland
  4. 4McKusick-Nathans Institute, Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland
  5. 5Department of Medicine, Baylor College of Medicine, Houston, Texas
  6. 6Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas
  7. 7Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas
  8. 8Department of Data Driven Medicine, Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany
  9. 9Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania
  10. 10Department of Medicine, The University of Mississippi Medical Center, Jackson, Mississippi
  11. 11Department of Medicine, New York University Langone School of Medicine, New York, New York
  1. Correspondence:
    Dr. Teresa K. Chen, 1830 East Monument Street, Suite 416, Baltimore, MD 21287. Email: tchen39{at}jhmi.edu

Funding

  • National Institute of Diabetes and Digestive and Kidney Diseases

    K08DK117068; P30DK079310; R01DK108803; R01DK24399
  • National Heart, Lung, and Blood Institute

    K24HL155861

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Clinical Journal of the American Society of Nephrology: 17 (5)
Clinical Journal of the American Society of Nephrology
Vol. 17, Issue 5
May 2022
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APOL1 Kidney Risk Variants and Proteomics
Teresa K. Chen, Aditya L. Surapaneni, Dan E. Arking, Christie M. Ballantyne, Eric Boerwinkle, Jingsha Chen, Josef Coresh, Anna Köttgen, Katalin Susztak, Adrienne Tin, Bing Yu, Morgan E. Grams
CJASN May 2022, 17 (5) 684-692; DOI: 10.2215/CJN.14701121

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APOL1 Kidney Risk Variants and Proteomics
Teresa K. Chen, Aditya L. Surapaneni, Dan E. Arking, Christie M. Ballantyne, Eric Boerwinkle, Jingsha Chen, Josef Coresh, Anna Köttgen, Katalin Susztak, Adrienne Tin, Bing Yu, Morgan E. Grams
CJASN May 2022, 17 (5) 684-692; DOI: 10.2215/CJN.14701121
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Keywords

  • AASK (African American Study of Kidney Disease and Hypertension)
  • chronic kidney disease
  • end stage kidney disease
  • epidemiology and outcomes
  • genetic renal disease
  • renal function decline
  • proteomics
  • apolipoprotein L1

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