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Original ArticlesCystic Kidney Disease
Open Access

Multicenter Study of Long-Term Safety of Tolvaptan in Later-Stage Autosomal Dominant Polycystic Kidney Disease

Vicente E. Torres, Arlene B. Chapman, Olivier Devuyst, Ron T. Gansevoort, Ronald D. Perrone, Jennifer Lee, Molly E. Hoke, Alvin Estilo and Olga Sergeyeva
CJASN January 2021, 16 (1) 48-58; DOI: https://doi.org/10.2215/CJN.10250620
Vicente E. Torres
1Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota
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Arlene B. Chapman
2Section of Nephrology, The University of Chicago School of Medicine, Chicago, Illinois
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Olivier Devuyst
3Institute of Physiology, University of Zurich, Zurich, Switzerland
4Division of Nephrology, Université Catholique de Louvain Medical School, Brussels, Belgium
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Ron T. Gansevoort
5Division of Nephrology, University Medical Center Groningen, Groningen, The Netherlands
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Ronald D. Perrone
6Division of Nephrology, Department of Medicine, Tufts Medical Center, Boston, Massachusetts
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Jennifer Lee
7Biostatistics, Otsuka Pharmaceutical Development & Commercialization, Rockville, Maryland
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Molly E. Hoke
8Global Medical Affairs, Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey
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Alvin Estilo
9Clinical Safety and Pharmacovigilance, Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey
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Olga Sergeyeva
10Global Clinical Development, Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey
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Article Information

vol. 16 no. 1 48-58
DOI 
https://doi.org/10.2215/CJN.10250620
PubMed 
33376102

Published By 
American Society of Nephrology
Print ISSN 
1555-9041
Online ISSN 
1555-905X
History 
  • Received June 23, 2020
  • Accepted October 29, 2020
  • Published online January 7, 2021.

Article Versions

  • Earlier version (December 29, 2020 - 08:13).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2021 by the American Society of Nephrology

Author Information

  1. Vicente E. Torres1,
  2. Arlene B. Chapman2,
  3. Olivier Devuyst3,4,
  4. Ron T. Gansevoort5,
  5. Ronald D. Perrone6,
  6. Jennifer Lee7,
  7. Molly E. Hoke8,
  8. Alvin Estilo9,
  9. Olga Sergeyeva10
  1. 1Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota
  2. 2Section of Nephrology, The University of Chicago School of Medicine, Chicago, Illinois
  3. 3Institute of Physiology, University of Zurich, Zurich, Switzerland
  4. 4Division of Nephrology, Université Catholique de Louvain Medical School, Brussels, Belgium
  5. 5Division of Nephrology, University Medical Center Groningen, Groningen, The Netherlands
  6. 6Division of Nephrology, Department of Medicine, Tufts Medical Center, Boston, Massachusetts
  7. 7Biostatistics, Otsuka Pharmaceutical Development & Commercialization, Rockville, Maryland
  8. 8Global Medical Affairs, Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey
  9. 9Clinical Safety and Pharmacovigilance, Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey
  10. 10Global Clinical Development, Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey
  1. Correspondence:
    Dr. Vicente E. Torres, Division of Nephrology and Hypertension, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905. Email: torres.vicente{at}mayo.edu
View Abstract

Funding

  • Otsuka Pharmaceutical

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Clinical Journal of the American Society of Nephrology: 16 (1)
Clinical Journal of the American Society of Nephrology
Vol. 16, Issue 1
January 07, 2021
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Multicenter Study of Long-Term Safety of Tolvaptan in Later-Stage Autosomal Dominant Polycystic Kidney Disease
Vicente E. Torres, Arlene B. Chapman, Olivier Devuyst, Ron T. Gansevoort, Ronald D. Perrone, Jennifer Lee, Molly E. Hoke, Alvin Estilo, Olga Sergeyeva
CJASN Jan 2021, 16 (1) 48-58; DOI: 10.2215/CJN.10250620

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Multicenter Study of Long-Term Safety of Tolvaptan in Later-Stage Autosomal Dominant Polycystic Kidney Disease
Vicente E. Torres, Arlene B. Chapman, Olivier Devuyst, Ron T. Gansevoort, Ronald D. Perrone, Jennifer Lee, Molly E. Hoke, Alvin Estilo, Olga Sergeyeva
CJASN Jan 2021, 16 (1) 48-58; DOI: 10.2215/CJN.10250620
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