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Original ArticlesAcute Kidney Injury and ICU Nephrology
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Prospective Cohort Study of Renin-Angiotensin System Blocker Usage after Hospitalized Acute Kidney Injury

Sandeep Brar, Kathleen D. Liu, Alan S. Go, Raymond K. Hsu, Vernon M. Chinchilli, Steven G. Coca, Amit X. Garg, Jonathan Himmelfarb, T. Alp Ikizler, James Kaufman, Paul L. Kimmel, Chirag R. Parikh, Edward D. Siew, Lorraine B. Ware, Hui Zeng, Chi-yuan Hsu and for the ASsessment, Serial Evaluation, and Subsequent Sequelae in Acute Kidney Injury (ASSESS-AKI) study investigators
CJASN January 2021, 16 (1) 26-36; DOI: https://doi.org/10.2215/CJN.10840720
Sandeep Brar
1Department of Epidemiology and Biostatistics, University of California, San Francisco, California
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Kathleen D. Liu
2Departments of Medicine and Anesthesia, University of California, San Francisco, California
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Alan S. Go
3Division of Nephrology, University of California, San Francisco School of Medicine, San Francisco, California
4Division of Research, Kaiser Permanente Northern California, Oakland, California
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Raymond K. Hsu
3Division of Nephrology, University of California, San Francisco School of Medicine, San Francisco, California
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  • ORCID record for Raymond K. Hsu
Vernon M. Chinchilli
5Department of Public Health Sciences, Pennsylvania State University College of Medicine, Hershey, Pennsylvania
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Steven G. Coca
6Division of Nephrology, Icahn School of Medicine at Mount Sinai, New York, New York
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  • ORCID record for Steven G. Coca
Amit X. Garg
7Department of Medicine, Epidemiology and Biostatistics, Western University, London, Ontario, Canada
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Jonathan Himmelfarb
8Division of Nephrology, University of Washington, Seattle, Washington
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T. Alp Ikizler
9Division of Nephrology and Hypertension and Vanderbilt Center for Kidney Disease, Vanderbilt University Medical Center, Nashville, Tennessee
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  • ORCID record for T. Alp Ikizler
James Kaufman
10Renal Section, Veterans Affairs New York Harbor Healthcare System and New York University School of Medicine, New York, New York
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Paul L. Kimmel
11Division of Kidney, Urologic and Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland
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Chirag R. Parikh
12Division of Nephrology, Johns Hopkins School of Medicine, Baltimore, Maryland
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Edward D. Siew
9Division of Nephrology and Hypertension and Vanderbilt Center for Kidney Disease, Vanderbilt University Medical Center, Nashville, Tennessee
13Tennessee Valley Health Services Nashville Veterans Affairs Hospital, Nashville, Tennessee
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Lorraine B. Ware
14Departments of Medicine and Pathology, Microbiology and Immunology, Vanderbilt University, Nashville, Tennessee
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Hui Zeng
5Department of Public Health Sciences, Pennsylvania State University College of Medicine, Hershey, Pennsylvania
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Chi-yuan Hsu
3Division of Nephrology, University of California, San Francisco School of Medicine, San Francisco, California
4Division of Research, Kaiser Permanente Northern California, Oakland, California
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Article Information

vol. 16 no. 1 26-36
DOI 
https://doi.org/10.2215/CJN.10840720
PubMed 
33272913

Published By 
American Society of Nephrology
Print ISSN 
1555-9041
Online ISSN 
1555-905X
History 
  • Received July 3, 2020
  • Accepted October 5, 2020
  • Published online January 7, 2021.

Article Versions

  • Earlier version (December 3, 2020 - 09:20).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2021 by the American Society of Nephrology

Author Information

  1. Sandeep Brar1,
  2. Kathleen D. Liu2,
  3. Alan S. Go3,4,
  4. Raymond K. Hsu3,
  5. Vernon M. Chinchilli5,
  6. Steven G. Coca6,
  7. Amit X. Garg7,
  8. Jonathan Himmelfarb8,
  9. T. Alp Ikizler9,
  10. James Kaufman10,
  11. Paul L. Kimmel11,
  12. Chirag R. Parikh12,
  13. Edward D. Siew9,13,
  14. Lorraine B. Ware14,
  15. Hui Zeng5,
  16. Chi-yuan Hsu3,4,
  17. for the ASsessment, Serial Evaluation, and Subsequent Sequelae in Acute Kidney Injury (ASSESS-AKI) study investigators*
  1. 1Department of Epidemiology and Biostatistics, University of California, San Francisco, California
  2. 2Departments of Medicine and Anesthesia, University of California, San Francisco, California
  3. 3Division of Nephrology, University of California, San Francisco School of Medicine, San Francisco, California
  4. 4Division of Research, Kaiser Permanente Northern California, Oakland, California
  5. 5Department of Public Health Sciences, Pennsylvania State University College of Medicine, Hershey, Pennsylvania
  6. 6Division of Nephrology, Icahn School of Medicine at Mount Sinai, New York, New York
  7. 7Department of Medicine, Epidemiology and Biostatistics, Western University, London, Ontario, Canada
  8. 8Division of Nephrology, University of Washington, Seattle, Washington
  9. 9Division of Nephrology and Hypertension and Vanderbilt Center for Kidney Disease, Vanderbilt University Medical Center, Nashville, Tennessee
  10. 10Renal Section, Veterans Affairs New York Harbor Healthcare System and New York University School of Medicine, New York, New York
  11. 11Division of Kidney, Urologic and Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland
  12. 12Division of Nephrology, Johns Hopkins School of Medicine, Baltimore, Maryland
  13. 13Tennessee Valley Health Services Nashville Veterans Affairs Hospital, Nashville, Tennessee
  14. 14Departments of Medicine and Pathology, Microbiology and Immunology, Vanderbilt University, Nashville, Tennessee
    1. Correspondence:
      Dr. Chi-yuan Hsu, Division of Nephrology, University of California, San Francisco School of Medicine, 533 Parnassus Avenue, U-400, Box 0532 San Francisco, CA 94143-0532. Email: chi-yuan.hsu{at}ucsf.edu
    1. ↵* The ASSESS-AKI Investigators are James Kaufman (Chair, Steering Committee; New York University School of Medicine); Vernon M. Chinchilli, Nasrollah Ghahramani, W. Brian Reeves, Lan Kong, Ming Wang, and Elana Farace (Data Coordinating Center; Pennsylvania State University); Alan Go, Chi-yuan Hsu, Kathleen Liu, Raymond Hsu, Thida Tan, Juan D. Ordonez, and Sijie Zheng (Kaiser Permanente Northern California/University of California, San Francisco); T. Alp Ikizler, Edward D. Siew, Julia B. Lewis, and Lorraine Ware (Vanderbilt University); Chirag Parikh, Steven Coca, and Dennis G. Moledina (Yale University); Amit X. Garg (Western University); Prasad Devarajan (Cincinnati Children's Hospital); Michael Zappitelli (McGill University); Jonathan Himmelfarb and Mark Wurfel (University of Washington); Paul L. Kimmel, Paul W. Eggers, and Marva M. Moxey-Mims (National Institute of Diabetes and Digestive and Kidney Diseases).

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    Funding

    • NIDDK

      U01DK082223; U01DK082185; U01DK082192; U01DK082183
    • NIDDK

      R01DK098233; R01DK101507; R01DK114014; R03DK111881; K24DK92291; K24DK113381

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    Clinical Journal of the American Society of Nephrology: 16 (1)
    Clinical Journal of the American Society of Nephrology
    Vol. 16, Issue 1
    January 07, 2021
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    Prospective Cohort Study of Renin-Angiotensin System Blocker Usage after Hospitalized Acute Kidney Injury
    Sandeep Brar, Kathleen D. Liu, Alan S. Go, Raymond K. Hsu, Vernon M. Chinchilli, Steven G. Coca, Amit X. Garg, Jonathan Himmelfarb, T. Alp Ikizler, James Kaufman, Paul L. Kimmel, Chirag R. Parikh, Edward D. Siew, Lorraine B. Ware, Hui Zeng, Chi-yuan Hsu, for the ASsessment, Serial Evaluation, and Subsequent Sequelae in Acute Kidney Injury (ASSESS-AKI) study investigators
    CJASN Jan 2021, 16 (1) 26-36; DOI: 10.2215/CJN.10840720

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    Prospective Cohort Study of Renin-Angiotensin System Blocker Usage after Hospitalized Acute Kidney Injury
    Sandeep Brar, Kathleen D. Liu, Alan S. Go, Raymond K. Hsu, Vernon M. Chinchilli, Steven G. Coca, Amit X. Garg, Jonathan Himmelfarb, T. Alp Ikizler, James Kaufman, Paul L. Kimmel, Chirag R. Parikh, Edward D. Siew, Lorraine B. Ware, Hui Zeng, Chi-yuan Hsu, for the ASsessment, Serial Evaluation, and Subsequent Sequelae in Acute Kidney Injury (ASSESS-AKI) study investigators
    CJASN Jan 2021, 16 (1) 26-36; DOI: 10.2215/CJN.10840720
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    Keywords

    • acute renal failure
    • renin angiotensin system
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    • acute kidney injury

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